Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.78 |
| ▸ | MAOA | P21397 | 3/20 | 0.78 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.78 |
| ▸ | PPARA | Q07869 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1070381 | 1.00 | MAOB (0.78) | MAOBMAOASCN9APPARA | |
| SCHEMBL2933427 | 0.88 | MAOB (0.81) | MAOBMAOASCN9APPARA | |
| SCHEMBL2933423 | 0.88 | MAOB (0.81) | MAOBMAOASCN9APPARA | |
| SCHEMBL14329886 | 0.88 | MAOB (0.81) | MAOBMAOASCN9APPARA | |
| Safinamide SCHEMBL194169 | 0.87 | MAOB (1.00) | MAOBMAOASCN9A | |
| Safinamide SCHEMBL31174565 | 0.87 | MAOB (1.00) | MAOBMAOASCN9A | |
| Safinamide SCHEMBL69350 | 0.87 | MAOB (1.00) | MAOBMAOASCN9A | |
| SCHEMBL29086940 | 0.87 | MAOB (0.83) | MAOBMAOASCN9A | |
| Safinamide SCHEMBL29358109 | 0.87 | MAOB (1.00) | MAOBMAOASCN9A | |
| SCHEMBL29086941 | 0.87 | MAOB (0.83) | MAOBMAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710040-B2 | Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2014-04-29 | — | — | US | claimed |
| US-20120142777-A1 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN ALPHA-AMINOAMIDE AND ITS ANALGESIC USE | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2012-06-07 | — | — | US | claimed |
| US-8084447-B2 | Synergistic pain treatment, side effect reduction; a mixture of pregabalin or tiagabine and 2-[4-(2-fluorobenzyloxy) benzylamino] propanamide | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2011-12-27 | — | — | US | claimed |
| EP-1423168-B1 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN ALPHA-AMINOAMIDE AND ITS ANALGESIC USE | NEWRON PHARM SPA (IT) | 2006-02-08 | — | — | EP | claimed |
| WO-2005070405-A1 | ALPHA-AMINOAMIDE DERIVATIVES USEFUL IN THE TREATMENT OF LOWER URINARY TRACT DISORDERS | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2005-08-04 | — | — | WO | claimed |
| EP-1557166-A1 | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders | Newron Pharmaceuticals S.p.A. (IT) | 2005-07-27 | — | — | EP | claimed |
| US-20040248978-A1 | Pharmaceutical composition comprising gabapentin or an analogue thereof and an aminoamide and its analgesic use | NEWRON PHARMACEUTICALS SPA (IT) | 2004-12-09 | — | — | US | claimed |
| EP-1423168-A2 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN $G(A)-AMINOAMIDE AND ITS ANALGESIC USE | Newron Pharmaceuticals S.p.A. (IT) | 2004-06-02 | — | — | EP | claimed |
| WO-2003020273-A2 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN $G(A)-AMINOAMIDE AND ITS ANALGESIC USE | NEWRON PHARMACEUTICALS SPA (IT) | 2003-03-13 | — | — | WO | claimed |
| US-8710040-B2 | Pharmaceutical composition comprising gabapentin or an analogue thereof and an α-aminoamide and its analgesic use | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2014-04-29 | — | — | US | disclosed |
| US-8487008-B2 | Treatment of muscular dystrophies and associated conditions by administration of monoamine oxidase inhibitors | UNIVERSITA DEGLI STUDI DI PADOVA (IT) | 2013-07-16 | — | — | US | disclosed |
| US-20120142777-A1 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN ALPHA-AMINOAMIDE AND ITS ANALGESIC USE | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2012-06-07 | — | — | US | disclosed |
| US-8084447-B2 | Synergistic pain treatment, side effect reduction; a mixture of pregabalin or tiagabine and 2-[4-(2-fluorobenzyloxy) benzylamino] propanamide | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2011-12-27 | — | — | US | disclosed |
| US-7718815-B2 | Alpha-aminoamide derivatives useful in the treatment of lower urinary tract disorders | NEWRON PHARMACEUTICALS S.P.A. (IT) | 2010-05-18 | — | — | US | disclosed |
| EP-1423168-A2 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN $G(A)-AMINOAMIDE AND ITS ANALGESIC USE | Newron Pharmaceuticals S.p.A. (IT) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003020273-A2 | PHARMACEUTICAL COMPOSITION COMPRISING GABAPENTIN OR AN ANALOGUE THEREOF AND AN $G(A)-AMINOAMIDE AND ITS ANALGESIC USE | NEWRON PHARMACEUTICALS SPA (IT) | 2003-03-13 | — | — | WO | disclosed |
| EP-0842143-B1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | NEWRON PHARM SPA (IT) | 2001-06-13 | — | — | EP | disclosed |
| US-5945454-A | 2-(4-substituted)-benzylamino-2-methyl-propanamide derivatives | PHARMACIA & UPJOHN, S.P.A. (IT) | 1999-08-31 | — | — | US | disclosed |
| EP-0842143-A1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997005102-A1 | 2-(4-SUBSTITUTED)-BENZYLAMINO-2-METHYL-PROPANAMIDE DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1997-02-13 | — | — | WO | disclosed |