⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190868 | 0.82 | — | — | |
| SCHEMBL29529965 | 0.82 | — | — | |
| SCHEMBL5700078 | 0.79 | — | — | |
| SCHEMBL31168148 | 0.79 | — | — | |
| SCHEMBL20043 | 0.78 | HTT (0.50) | — | |
| SCHEMBL29546988 | 0.78 | HTT (0.50) | — | |
| SCHEMBL1043905 | 0.77 | — | — | |
| SCHEMBL16619004 | 0.77 | — | — | |
| SCHEMBL31133690 | 0.76 | HTT (0.48) | — | |
| SCHEMBL21408192 | 0.75 | KMT2A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 406 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117778359-A | Nitrilase mutant and method for biocatalysis co-production of chloronicotinic acid | 浙江工业大学 | 2024-03-29 | — | — | CN | claimed |
| CN-210855910-U | Purification device of 2 chlorine nicotinonitrile | 江苏三鹏生物化工有限公司 | 2020-06-26 | — | — | CN | claimed |
| CN-111153825-A | Method for preparing amide compound by using supported metal oxide catalytic material | 浙江大学 | 2020-05-15 | — | — | CN | claimed |
| CN-104829525-B | A kind of continuous reaction produces the method for the chloro-nicotinonitrile of 2- | Positive biochemical company limited in Jiangsu (CN) | 2016-02-24 | — | — | CN | claimed |
| CN-104829525-A | Method for producing 2-chloro-3-cyanopyridine through continuous reaction | JIANGSU ZHONGZHENG BIOCHEMICAL CO LTD | 2015-08-12 | — | — | CN | claimed |
| CN-104592104-A | Method for preparing 2-chloronicotinic acid | JIANGSU ZHONGBANG PHARMACEUTICAL CO LTD | 2015-05-06 | — | — | CN | claimed |
| CN-104557925-A | Preparation method of pyrazolopyridine derivative | Hunan huateng pharmaceutical co ltd | 2015-04-29 | — | — | CN | claimed |
| EP-4719394-A2 | INHIBITORS OF TYK2 | Atomwise Inc. (US) | 2026-04-08 | — | — | EP | disclosed |
| US-20260048051-A1 | TREATMENT OF INFLAMMATORY BOWEL DISEASE | ATOMWISE INC (US) | 2026-02-19 | — | — | US | disclosed |
| US-12545682-B2 | Heterocyclic derivatives as P2X7 receptor antagonists | BREYE THERAPEUTICS APS (DK) | 2026-02-10 | — | — | US | disclosed |
| US-12508268-B2 | Inhibitors of tryptophan dioxygenases (IDO1 and TDO) and their use in therapy | AUCKLAND UNISERVICES LIMITED (NZ) | 2025-12-30 | — | — | US | disclosed |
| US-20250388615-A9 | SUBSTITUTED 4-PHENYL PYRIDINE COMPOUNDS AS NON-SYSTEMIC TGR5 AGONISTS | ARDELYX, INC. (US) | 2025-12-25 | — | — | US | disclosed |
| EP-4638448-A1 | CONJUGATES COMPRISING ANTIFUNGALS AND CASEIN KINASE (CK1) INHIBITORS AND METHODS OF USE THEREOF | Bright Angel Therapeutics Inc. (CA) | 2025-10-29 | — | — | EP | disclosed |
| US-6218385-B1 | FOR THERAPY OR PROPHYLAXIS OF ACUTE AND/OR CHRONIC NEUROLOGICAL DISORDERS SUCH AS EPILEPSY, STROKE, CHRONIC AND ACUTE PAIN, PSYCHOSIS, SCHIZOPHRENIA, ALZHEIMER'S DISEASE, COGNITIVE DISORDERS AND MEMORY DEFICITS | HOFFMANN-LA ROCHE INC. | 2001-04-17 | — | — | US | disclosed |
| EP-1074549-A2 | Tetrahydro-benzo(d)azepines and their use as antagonists at metabotropic glutamate receptors | F. HOFFMANN-LA ROCHE AG (CH) | 2001-02-07 | — | — | EP | disclosed |
| EP-1020445-A1 | FUSED PYRIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 2000-07-19 | — | — | EP | disclosed |
| EP-0808318-B1 | TRICYCLIC SUBSTITUTED HEXAHYDROBENZ[E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS | ABBOTT LAB (US) | 2000-06-28 | — | — | EP | disclosed |
| US-5597823-A | TREATING BENIGN PROSTATIC HYPERPLASIA | ABBOTT LABORATORIES (US) | 1997-01-28 | — | — | US | disclosed |
| WO-1996022992-A1 | TRICYCLIC SUBSTITUTED HEXAHYDROBENZ[E]ISOINDOLE ALPHA-1 ADRENERGIC ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-08-01 | — | — | WO | disclosed |
| EP-0192287-A2 | Process for the preparation of fluorinated pyridines | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-08-27 | — | — | EP | disclosed |