⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290092 | 0.90 | — | — | |
| SCHEMBL2263408 | 0.71 | — | — | |
| SCHEMBL4480046 | 0.67 | — | — | |
| SCHEMBL8085814 | 0.66 | CYP2C19 (0.32) | — | |
| SCHEMBL352623 | 0.65 | — | — | |
| SCHEMBL4487623 | 0.65 | — | — | |
| SCHEMBL4598251 | 0.64 | — | — | |
| SCHEMBL5157792 | 0.64 | — | — | |
| SCHEMBL6000952 | 0.62 | — | — | |
| SCHEMBL7510179 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727287-B2 | Hemicyanin styryl thiol/disulfide dye, composition comprising hemicyanin styryl thoil/disulfide dye, and method for lightening keratin materials using hemicyanin styryl thiol/disulfide dye | L'OREAL S.A. (FR) | 2010-06-01 | — | — | US | disclosed |
| US-20090211038-A1 | HEMICYANIN STYRYL THIOL/DISULFIDE DYE, COMPOSITION COMPRISING HEMICYANIN STYRYL THIOL/DISULFIDE DYE, AND METHOD FOR LIGHTENING KERATIN MATERIALS USING HEMICYANIN STYRYL THIOL/DISULFIDE DYE | L'OREAL S.A. (FR) | 2009-08-27 | — | — | US | disclosed |
| EP-2062945-A2 | Hemicyanin styryl thiol/disulfide dye, dye composition comprising this dye, process for lightening keratin materials using this dye | L'Oréal (FR) | 2009-05-27 | — | — | EP | disclosed |
| US-20050026929-A1 | Novel phenyl derivatives as inducers of apoptosis | AXYS PHARMACEUTICALS, INC. (US) | 2005-02-03 | — | — | US | disclosed |
| EP-0325268-B1 | 1,4-DISUBSTITUTED-PIPERIDINYL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1993-06-02 | — | — | EP | disclosed |
| US-5162342-A | USE OF 1,4-DISUBSTITUTED-PIPERIDINYL COMPOUNDS FOR ANALGESIA AND MUSCLE RELAXATION | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5064838-A | 1,4-DISUBSTITUTED-PIPERIDINYL COMPOUNDS AS PAIN RELIEVERS | MERRELL DOW PHARMACEUTICALS (US) | 1991-11-12 | — | — | US | disclosed |
| EP-0325268-A1 | 1,4-Disubstituted-piperidinyl compounds | MERRELL DOW PHARMACEUTICALS INC. (US) | 1989-07-26 | — | — | EP | disclosed |