SCHEMBL3291003

SCHEMBL3291003

C=C(C)C(=O)OC(C)S(=O)(=O)CC

nearest known ligand 0.44

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.44
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5872176 0.87 TSHR (0.40) TSHRALDH1A1THRB
SCHEMBL29323720 0.85 TSHR (0.46) TSHRALDH1A1THRB
SCHEMBL5872290 0.84 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL5872131 0.83 TSHR (0.45) TSHR
SCHEMBL22438 0.79 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL5872388 0.79 TSHR (0.42) TSHRALDH1A1THRB
SCHEMBL434884 0.78 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL8861465 0.78 TSHR (0.41) TSHRALDH1A1THRB
Ammonia Solution, Strong SCHEMBL8861520 0.78 TSHR (0.41) TSHRALDH1A1THRB
SCHEMBL8861430 0.78 TSHR (0.41) TSHRALDH1A1THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108132726-B Touch sensitive element and display device comprising same 乐金显示有限公司 2021-05-25 CN claimed
US-6559198-B2 A contact lens comprising a copolymer consisting essentially of from about 25 to about 60 weight percent of a ethylenically unsaturated fluorosulfone ester monomer having the general formula comonomer selected from the group consisting of NOVICKY NICK (CA) 2003-05-06 US claimed
US-20030027886-A1 Fluorocarbon-sulfone hydrophilic contact lenses, optical medical devices and compositions thereof NOVICKY NICK (CA) 2003-02-06 US claimed
EP-0231572-B1 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RES LTD (CA) 1994-11-02 EP claimed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US claimed
EP-0231572-A2 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RESEARCH LTD. (CA) 1987-08-12 EP claimed
EP-3515402-B1 (METH)ACRYLATE BASED RESIN BINDER COMPOSITION ROEHM AMERICA LLC (US) 2024-11-27 EP disclosed
CN-114174238-B Low odor and low emission particulate materials and related coatings 赛德克公众有限公司 2023-05-05 CN disclosed
CN-109789078-B (meth) acrylate-based resin binder composition 赢创有限公司 2022-10-04 CN disclosed
US-11279832-B2 (Meth)acrylate based resin binder composition ROEHM GMBH (DE) 2022-03-22 US disclosed
CN-114174238-A Particulate materials and related coatings, especially architectural element coatings, with low odor and low emissions, e.g. floor coatings based on free radical polymerization 赛德克公众有限公司 2022-03-11 CN disclosed
CN-109071736-B Graft copolymers based on a polyolefin backbone and methacrylate side chains 赢创运营有限公司 2021-08-10 CN disclosed
EP-3455266-B1 GRAFT COPOLYMERS BASED ON POLYOLEFIN BACKBONE AND METHACRYLATE SIDE CHAINS EVONIK OPERATIONS GMBH (DE) 2020-10-28 EP disclosed
EP-0231572-B1 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RES LTD (CA) 1994-11-02 EP disclosed
US-5093447-A Contact lenses NOVICKY NICK N (CA) 1992-03-03 US disclosed
US-4948855-A COPOLYMER OF UNSATURATED SILOXANYLALKOXYESTER AND VINYL SILFONE PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) 1990-08-14 US disclosed
US-4861850-A CONTACT LENSES PROGRESSIVE CHEMICAL RESEARCH, LTD. (CA) 1989-08-29 US disclosed
US-4748224-A Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof Devou, Maureen J. (CA) 1988-05-31 US disclosed
US-4743106-A POLYMER HAVING AN ORGANOSILOXANYLALKOXY ESTER OF (METH)ACRYLIC ACID MONOMER; MACHINING Devou, Maureen J. (CA) 1988-05-10 US disclosed
EP-0231572-A2 Silicone-sulfone and silicone-fluorocarbon-sulfone gas permeable contact lenses and compositions thereof PROGRESSIVE OPTICAL RESEARCH LTD. (CA) 1987-08-12 EP disclosed