SCHEMBL329345

SCHEMBL329345

[O]c1cccc(Cl)c1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23239 0.77
SCHEMBL3991309 0.77 TSHR (0.61)
SCHEMBL28536708 0.75 TSHR (0.52)
SCHEMBL57842 0.75
Fluoride SCHEMBL28376896 0.74 TSHR (0.58)
Phosphine SCHEMBL22230521 0.74 TSHR (0.58)
SCHEMBL10786340 0.74 TSHR (0.58)
SCHEMBL1395277 0.74 TSHR (0.58)
Hydrochloric Acid SCHEMBL31618288 0.74 TSHR (0.58)
SCHEMBL3645067 0.74 TSHR (0.58)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1005 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118215676-A Specific conjugation of antibody drug conjugates 杭州多禧生物科技有限公司 2024-06-18 CN claimed
CN-117980327-A Specific coupling of antibodies 杭州多禧生物科技有限公司 2024-05-03 CN claimed
WO-2024033388-A1 BICYCLIC TETRAHYDROTHIAZEPINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2024-02-15 WO claimed
US-11779663-B2 Specific conjugation linkers, specific immunoconjugates thereof, methods of making and uses such conjugates thereof HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-10-10 US claimed
CN-114539086-B Synthesis method of diclofenac sodium 复旦大学 2023-10-03 CN claimed
US-20230241241-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-08-03 US claimed
CN-116143678-A Conjugate linker, cell-binding molecule-drug conjugate containing the same, and preparation and application thereof 杭州多禧生物科技有限公司 2023-05-23 CN claimed
WO-2023078021-A1 BCMA MONOCLONAL ANTIBODY AND THE ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO claimed
WO-2023078273-A1 SPECIFIC CONJUGATION FOR AN ANTIBODY-DRUG CONJUGATE HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-05-11 WO claimed
EP-4168009-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS Hangzhou DAC Biotech Co., Ltd. (CN) 2023-04-26 EP claimed
US-4537979-A Alpha-substituted-alkylarylketals particularly useful for preparing alpha-arylalkanoic acids ZAMBON S.P.A. (IT) 1985-08-27 US claimed
US-4535166-A Process for preparing alpha-arylalkanoic acids ZAMBON S.P.A. (IT) 1985-08-13 US claimed
EP-0135198-A2 Process for dyeing synthetic polyamide fibrous material CIBA-GEIGY AG (CH) 1985-03-27 EP claimed
US-4444564-A Process for dyeing fiber material made of natural polyamides with anionic wool dyes at pH 4.5 to 5.5 in the presence of a dyeing assistant CIBA-GEIGY CORPORATION (US) 1984-04-24 US claimed
EP-0089004-A1 Process for dyeing fibrous material from natural polyamides CIBA-GEIGY AG (CH) 1983-09-21 EP claimed
EP-0054974-A1 Imidazolylpropanol compounds and their acid addition salts, and production and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1982-06-30 EP claimed
US-4256635-A BASIC MONOAZO DYES SANDOZ LTD. (CH) 1981-03-17 US claimed
US-4186243-A AZO COLOR FORMER AND CLAY ACTIVATOR CIBA-GEIGY CORPORATION (US) 1980-01-29 US claimed
US-4131695-A Azo color former containing heat-sensitive recording material CIBA-GEIGY CORPORATION (US) 1978-12-26 US claimed
US-3998805-A MONOAZO DYES; POLYESTERS; YELLOW, RED, OR ORANGE SHADES CIBA-GEIGY CORPORATION (US) 1976-12-21 US claimed