Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866536 | 0.98 | TSHR (0.50) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| SCHEMBL29583483 | 0.98 | TSHR (0.50) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| SCHEMBL6659835 | 0.98 | TSHR (0.50) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| Triphenyl Phosphate SCHEMBL28329677 | 0.98 | TSHR (0.50) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3297919 | 0.96 | TSHR (0.48) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| SCHEMBL23802680 | 0.91 | CYP3A4 (0.63) | TSHRCYP3A4SRCTDP1MEN1 | |
| SCHEMBL38652229 | 0.89 | MEN1 (0.42) | TSHRCYP3A4SRCKDM4EL3MBTL1 | |
| SCHEMBL29405980 | 0.88 | KDM4E (0.50) | TSHRCYP3A4KDM4ETDP1MEN1 | |
| SCHEMBL35762 | 0.88 | KDM4E (0.50) | TSHRCYP3A4KDM4ETDP1MEN1 | |
| Triphenyl Phosphate SCHEMBL28878578 | 0.88 | SRC (0.58) | TSHRCYP3A4SRCKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7737244-B2 | Process for preparing polyarylate | LG CHEM, LTD. (KR) | 2010-06-15 | — | — | US | claimed |
| US-20090036634-A1 | Process for Preparing Polyarylate | SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) | 2009-02-05 | — | — | US | claimed |
| WO-2007094638-A1 | PROCESS FOR PREPARING POLYARYLATE | LG CHEM, LTD. (KR) | 2007-08-23 | — | — | WO | claimed |
| US-7737244-B2 | Process for preparing polyarylate | LG CHEM, LTD. (KR) | 2010-06-15 | — | — | US | disclosed |
| US-20090036634-A1 | Process for Preparing Polyarylate | SHANJIN OPTOELECTRONICS (SUZHOU) CO., LTD. (CN) | 2009-02-05 | — | — | US | disclosed |
| WO-2007094638-A1 | PROCESS FOR PREPARING POLYARYLATE | LG CHEM, LTD. (KR) | 2007-08-23 | — | — | WO | disclosed |