⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16240415 | 1.00 | — | — | |
| SCHEMBL594504 | 1.00 | — | — | |
| SCHEMBL14647435 | 1.00 | — | — | |
| SCHEMBL8245300 | 1.00 | — | — | |
| SCHEMBL31285696 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL15689230 | 0.98 | GRM2 (0.61) | — | |
| SCHEMBL25660668 | 0.83 | GRM2 (0.59) | — | |
| SCHEMBL2790345 | 0.82 | — | — | |
| SCHEMBL1954837 | 0.82 | — | — | |
| SCHEMBL8274144 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028186-B1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM CA LTD (CA) | 2013-01-23 | — | — | EP | disclosed |
| US-RE41356-E1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM CANADA LTD. (CA) | 2010-05-25 | — | — | US | disclosed |
| EP-1105413-B1 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2009-04-29 | — | — | EP | disclosed |
| EP-2028186-A2 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2009-02-25 | — | — | EP | disclosed |
| US-RE40525-E1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2008-09-30 | — | — | US | disclosed |
| EP-1105422-B1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM CA LTD (CA) | 2006-02-15 | — | — | EP | disclosed |
| US-6767991-B1 | PEPTIDES AND ANALOGS THEREOF; VIRAL PROTEASE INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH PEPTIDES AND RIBAVIRIN | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2004-07-27 | — | — | US | disclosed |
| US-6420380-B2 | FOR TREATMENT OF HEPATITIS C VIRUS (HCV) INFECTION | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-07-16 | — | — | US | disclosed |
| US-6410531-B1 | FOR THERAPY OF HEPATITIS C VIRUS (HCV) INFECTION | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2002-06-25 | — | — | US | disclosed |
| US-20020037998-A1 | Hepatitis C inhibitor tri-peptides | LLINAS-BRUNET MONTSE (CA) | 2002-03-28 | — | — | US | disclosed |
| US-20020016442-A1 | Hepatitis C inhibitor tri-peptides | LLINAS-BRUNET MONTSE (CA) | 2002-02-07 | — | — | US | disclosed |
| US-6329417-B1 | RACEMATES, DIASTEREOISOMERS AND OPTICAL ISOMERS; PROTEASE INHIBITOR PEPTIDE ANALOG | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-12-11 | — | — | US | disclosed |
| US-6323180-B1 | PROTEASE INHIBITORS; INHIBIT REPLICATION OF HEPATITIS C VIRUS | BOEHRINGER INGELHEIM (CANADA) LTD (CA) | 2001-11-27 | — | — | US | disclosed |
| EP-1105422-A1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-13 | — | — | EP | disclosed |
| EP-1105413-A2 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000009558-A1 | HEPATITIS C INHIBITOR PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-02-24 | — | — | WO | disclosed |
| WO-2000009543-A2 | HEPATITIS C INHIBITOR TRI-PEPTIDES | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2000-02-24 | — | — | WO | disclosed |