⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505350 | 0.80 | — | — | |
| SCHEMBL4588217 | 0.78 | — | — | |
| SCHEMBL27260243 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL17361360 | 0.76 | — | — | |
| SCHEMBL244009 | 0.74 | — | — | |
| SCHEMBL3346700 | 0.74 | — | — | |
| SCHEMBL7079017 | 0.74 | — | — | |
| SCHEMBL7812654 | 0.74 | — | — | |
| SCHEMBL5383 | 0.74 | — | — | |
| SCHEMBL1185934 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317025-B | A kind of triazole class compounds containing trifluoromethyl pyrazol and preparation method thereof and its application | 浙江工业大学 | 2019-03-05 | — | — | CN | claimed |
| CN-103582631-B | The method for preparing the organic compound of fluorination | 罗地亚经营管理公司 | 2017-10-24 | — | — | CN | claimed |
| CN-106317025-A | Triazole compound containing trifluoromethyl pyrazol and preparation method and application thereof | 浙江工业大学 | 2017-01-11 | — | — | CN | claimed |
| CN-106234374-A | The application in preparing antibacterial of a kind of triazole class compounds containing trifluoromethyl pyrazol | 浙江工业大学 | 2016-12-21 | — | — | CN | claimed |
| US-9278935-B2 | Method for preparing a fluorinated organic compound | RHODIA OPERATIONS (FR) | 2016-03-08 | — | — | US | claimed |
| US-20140148603-A1 | Method for preparing a fluorinated organic compound | RHODIA OPERATIONS (FR) | 2014-05-29 | — | — | US | claimed |
| CN-103582631-A | Method for preparing a fluorinated organic compound | RHODIA OPERATIONS | 2014-02-12 | — | — | CN | claimed |
| WO-2012163905-A1 | METHOD FOR PREPARING A FLUORINATED ORGANIC COMPOUND | RHODIA OPERATIONS (FR) | 2012-12-06 | — | — | WO | claimed |
| WO-2012163896-A1 | METHOD FOR THE PREPARATION OF A FLUORO-METHYLPYRAZOLE COMPOUND IN CARBOXYLIC ACID OR DERIVATIVE FORM | RHODIA OPERATIONS (FR) | 2012-12-06 | — | — | WO | claimed |
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| CN-114195715-B | Process for preparing 1-methyl-3-difluoromethyl-4-pyrazole acid and 1-methyl-3-trifluoromethyl-4-pyrazole acid | 福建永晶科技股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |
| CN-117384096-A | Preparation method of difluoro pyrazole acid | 山东国邦药业有限公司 | 2024-01-12 | — | — | CN | disclosed |
| EP-3555070-B1 | AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND METHODS OF USE THEREOF | EPIZYME INC (US) | 2023-08-09 | — | — | EP | disclosed |
| CN-101195672-B | Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers | SUMITOMO CHEMICAL CO | 2011-07-06 | — | — | CN | disclosed |
| US-7732540-B2 | Process for producing olefin copolymerization catalyst and process for producing olefin copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-08 | — | — | US | disclosed |
| EP-1802621-B1 | CRF RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | SMITHKLINE BEECHAM CORK LTD (IE) | 2009-05-06 | — | — | EP | disclosed |
| US-20090018012-A1 | Process for Producing Olefin Copolymerization Catalyst and Process for Producing Olefin Copolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-15 | — | — | US | disclosed |
| CN-101195672-A | Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers | SUMITOMO CHEMICAL CO (JP) | 2008-06-11 | — | — | CN | disclosed |
| CN-1106386-C | Parasiticidal pyrazoles | PFIZER LTD (US) | 2003-04-23 | — | — | CN | disclosed |