⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290664 | 0.83 | — | — | |
| SCHEMBL1378337 | 0.74 | — | — | |
| SCHEMBL1380101 | 0.68 | — | — | |
| Hydrogen Sulfide SCHEMBL6282876 | 0.67 | — | — | |
| SCHEMBL6862975 | 0.66 | — | — | |
| SCHEMBL9058719 | 0.66 | — | — | |
| SCHEMBL1379647 | 0.60 | — | — | |
| SCHEMBL1379649 | 0.60 | — | — | |
| SCHEMBL1380269 | 0.57 | — | — | |
| SCHEMBL6855736 | 0.55 | TMEM97 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732507-B2 | Spirotetrathiocarbamates and spirooxothiocarbamates | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2010-06-08 | — | — | US | disclosed |
| US-20080103230-A1 | Spirotetrathiocarbamates and Spirooxothiocarbamates | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2008-05-01 | — | — | US | disclosed |
| EP-1581561-A2 | SPIROTETRATHIOCARBAMATES AND SPIROOXOTHIOCARBAMATES | ESSILOR INTERNATIONAL (Compagnie Générale d'Optique) (FR) | 2005-10-05 | — | — | EP | disclosed |
| WO-2004056879-A2 | SPIROTETRATHIOCARBAMATES AND SPIROOXOTHIOCARBAMATES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 2004-07-08 | — | — | WO | disclosed |