⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL128775 | 0.97 | TP53 (0.31) | — | |
| Hydrochloric Acid SCHEMBL28792672 | 0.97 | TP53 (0.31) | — | |
| SCHEMBL14955502 | 0.88 | TP53 (0.30) | — | |
| SCHEMBL28108473 | 0.87 | TP53 (0.35) | — | |
| SCHEMBL490947 | 0.85 | — | — | |
| SCHEMBL1507280 | 0.83 | — | — | |
| SCHEMBL4546739 | 0.83 | SLC22A6 (0.37) | — | |
| SCHEMBL490886 | 0.83 | TP53 (0.32) | — | |
| SCHEMBL1627316 | 0.83 | — | — | |
| SCHEMBL329281 | 0.83 | HDAC1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 286 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290499-A | Preparation method of netilmicin sulfate | 福建省福抗药业股份有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-106404736-A | Special detection method and equipment for estradiol in duck meat | 百奥森（江苏）食品安全科技有限公司 | 2017-02-15 | — | — | CN | claimed |
| EP-2610958-B1 | Non-aqueous electrolyte and electrochemical device comprising the same | LG CHEMICAL LTD (KR) | 2014-10-01 | — | — | EP | claimed |
| CN-101333227-B | Method for making alkoxy-modified silsesquioxanes | BRIDGESTONE CORP | 2013-08-21 | — | — | CN | claimed |
| EP-2269261-B1 | NON-AQUEOUS ELECTROLYTE SOLUTION AND ELECTROCHEMICAL DEVICE COMPRISING THE SAME | LG CHEMICAL LTD (KR) | 2013-05-01 | — | — | EP | claimed |
| CN-101333227-A | Method for making alkoxy-modified silsesquioxanes | BRIDGESTONE AMERICAS HOLDING I (JP) | 2008-12-31 | — | — | CN | claimed |
| US-20080317834-A1 | Compounds and methods for modulating cerebral amyloid angiopathy | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2008-12-25 | — | — | US | claimed |
| EP-1064013-A4 | $i(IN VITRO) FORMATION OF CONGOPHILIC MALTESE-CROSS AMYLOID PLAQUES TO IDENTIFY ANTI-PLAQUE THERAPEUTICS FOR THE TREATMENT OF ALZHEIMER'S AND PRION DISEASES | UNIV WASHINGTON (US) | 2005-05-11 | — | — | EP | claimed |
| JP-3623236-B2 | — | — | 2005-02-23 | — | — | JP | claimed |
| US-20040220138-A1 | Methods for modulating neuronal cell death | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-11-04 | — | — | US | claimed |
| US-20020022657-A1 | Methods for modulating neuronal cell death | NEUROCHEM (INTERNATIONAL) LIMITED (GI) | 2002-02-21 | — | — | US | claimed |
| WO-2001085093-A2 | COMPOUNDS AND METHODS FOR MODULATING CEREBRAL AMYLOID ANGIOPATHY | NEUROCHEM, INC. (US) | 2001-11-15 | — | — | WO | claimed |
| EP-1077690-A1 | USE OF AMYLOID INHIBITORS FOR MODULATING NEURONAL CELL DEATH | Neurochem, Inc. (CA) | 2001-02-28 | — | — | EP | claimed |
| EP-1064013-A1 | $i(IN VITRO) FORMATION OF CONGOPHILIC MALTESE-CROSS AMYLOID PLAQUES TO IDENTIFY ANTI-PLAQUE THERAPEUTICS FOR THE TREATMENT OF ALZHEIMER'S AND PRION DISEASES | University of Washington (US) | 2001-01-03 | — | — | EP | claimed |
| WO-1999045947-A9 | IN VITRO FORMATION OF CONGOPHILIC MALTESE-CROSS AMYLOID PLAQUES TO IDENTIFY ANTI-PLAQUE THERAPEUTICS FOR THE TREATMENT OF ALZHEIMER'S AND PRION DISEASES | UNIV WASHINGTON (US) | 2000-03-02 | — | — | WO | claimed |
| WO-1999059571-A1 | USE OF AMYLOID INHIBITORS FOR MODULATING NEURONAL CELL DEATH | NEUROCHEM, INC. (US) | 1999-11-25 | — | — | WO | claimed |
| WO-1999045947-A1 | IN VITRO FORMATION OF CONGOPHILIC MALTESE-CROSS AMYLOID PLAQUES TO IDENTIFY ANTI-PLAQUE THERAPEUTICS FOR THE TREATMENT OF ALZHEIMER'S AND PRION DISEASES | UNIVERSITY OF WASHINGTON (US) | 1999-09-16 | — | — | WO | claimed |
| US-5840294-A | INHIBITING AMYLOID DEPOSITION BY ADMINISTERING A THERAPEUTIC COMPOUND COMPRISING AN ANIONIC GROUP AND A CARRIER MOLECULE | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1998-11-24 | — | — | US | claimed |
| EP-0814842-A1 | METHOD FOR TREATING AMYLOIDOSIS | Queen's University at Kingston (CA) | 1998-01-07 | — | — | EP | claimed |
| WO-1996028187-A1 | METHOD FOR TREATING AMYLOIDOSIS | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 1996-09-19 | — | — | WO | claimed |