SCHEMBL3295754

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3291813	0.89	MAPK14 (0.56)	MAPK14MAPK9SMN1; SMN2MAPK13MAPK12
	SCHEMBL3293014	0.88	HPGD (0.52)	HPGDMAPK14MAPK9NTRK1SMN1; SMN2
	SCHEMBL3295310	0.87	HPGD (0.51)	HPGDMAPK14MAPK9NTRK1SMN1; SMN2
	SCHEMBL3300827	0.85	MAPK14 (0.54)	HPGDMAPK14MAPK9NTRK1MAPK13
	SCHEMBL3294771	0.84	MAPK14 (0.51)	HPGDMAPK14MAPK9NTRK1SMN1; SMN2
	SCHEMBL3299975	0.83	MAPK14 (0.59)	HPGDMAPK14MAPK9NTRK1SMN1; SMN2
	SCHEMBL3293302	0.83	HPGD (0.47)	HPGDMAPK14MAPK9NTRK1SMN1; SMN2
	SCHEMBL3301276	0.83	HPGD (0.50)	HPGDMAPK14MAPK9NTRK1MAPK13
	SCHEMBL3299366	0.81	MAPK14 (0.72)	MAPK14MAPK9NTRK1MAPK13MAPK12
	SCHEMBL3295881	0.81	MAPK14 (0.53)	HPGDMAPK14MAPK9NTRK1MAPK13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.