⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2079963 | 1.00 | AHR (0.44) | — | |
| SCHEMBL29882403 | 1.00 | — | — | |
| SCHEMBL28080236 | 0.70 | PIK3CD (0.37) | — | |
| SCHEMBL12470 | 0.70 | — | — | |
| SCHEMBL706764 | 0.70 | MAPT (0.50) | — | |
| SCHEMBL30205720 | 0.70 | — | — | |
| SCHEMBL29465576 | 0.70 | — | — | |
| SCHEMBL709416 | 0.70 | PDE3B (0.50) | — | |
| SCHEMBL67000 | 0.70 | — | — | |
| SCHEMBL17372872 | 0.69 | MAPT (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 418 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | claimed |
| CN-119841843-A | Compound combined with CRBN protein and degradation agent of CRBN protein | 中国海洋大学 | 2025-04-18 | — | — | CN | claimed |
| CN-109476666-A | Substituted pyrrolo [2,3-d ] pyridazin-4-ones and pyrazolo [3,4-d ] pyridazin-4-ones as kinase inhibitors | 上海复尚慧创医药研究有限公司 | 2019-03-15 | — | — | CN | claimed |
| CN-108367049-A | The combination preparation of PKM2 conditioning agents and HMGB1 | 海德堡吕布莱希特-卡尔斯大学 | 2018-08-03 | — | — | CN | claimed |
| CN-1170829-C | Optically active pyrrolopyridazine compound | ������������ʽ���� | 2004-10-13 | — | — | CN | claimed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | claimed |
| WO-2026103730-A1 | DIAZAHETEROCYCLIC DERIVATIVE OF PYRIDOARYL GROUP HAVING KAPPA RECEPTOR ANTAGONISTIC ACTIVITY AND COMPOSITION THEREOF, AND USE | 江苏恩华药业股份有限公司 | 2026-05-21 | — | — | WO | disclosed |
| US-12378255-B2 | Toll-like receptor antagonist compounds and methods of use | DYNAVAX TECHNOLOGIES CORPORATION (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250144093-A1 | PYRUVATE KINASE ACTIVATORS FOR USE IN TREATING BLOOD DISORDERS | AGIOS PHARMACEUTICALS, INC. | 2025-05-08 | — | — | US | disclosed |
| WO-2025082069-A1 | COMPOUND BINDING TO CRBN PROTEIN AND DEGRADATION AGENT OF PROTEIN | 中国海洋大学 | 2025-04-24 | — | — | WO | disclosed |
| CN-119841843-A | Compound combined with CRBN protein and degradation agent of CRBN protein | 中国海洋大学 | 2025-04-18 | — | — | CN | disclosed |
| US-12215105-B2 | HPK1 antagonists and uses thereof | Nimbus Saturn, Inc. (US) | 2025-02-04 | — | — | US | disclosed |
| US-12133853-B2 | Pyruvate kinase activators for use in treating blood disorders | AGIOS PHARMACEUTICALS, INC. (US) | 2024-11-05 | — | — | US | disclosed |
| CN-1370172-A | Optically active pyrrolopyridazine compound | SANKYO CO (JP) | 2002-09-18 | — | — | CN | disclosed |
| CN-1284078-A | Heterocyclic compounds for inhibiting gastric acid secretion, process for their preparation and pharmaceutical compositions containing them | ASTRA ZENECA LTD (SE) | 2001-02-14 | — | — | CN | disclosed |
| EP-1042324-A1 | HETEROCYCLIC COMPOUNDS FOR INHIBITION OF GASTRIC ACID SECRETION, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | AstraZeneca AB (SE) | 2000-10-11 | — | — | EP | disclosed |
| CN-1044811-C | Pyrrolopyridazine derivatives | SANKYO CO (JP) | 1999-08-25 | — | — | CN | disclosed |
| WO-1999028322-A1 | HETEROCYCLIC COMPOUNDS FOR INHIBITION OF GASTRIC ACID SECRETION, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS THEREOF | ASTRAZENECA AB (SE) | 1999-06-10 | — | — | WO | disclosed |
| CN-1143964-A | Pyrrolopyridazine derivative | SANKYO CO (JP) | 1997-02-26 | — | — | CN | disclosed |
| US-4871653-A | DEVELOPING IN PRESENCE OF MERCAPTO POLYAZAINDENE PROMOTERS AND NUCLEATING QUATERNARY OR HYDRAZIDE-TYPE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1989-10-03 | — | — | US | disclosed |