Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23901170 | 0.89 | CA14 (0.36) | CA14HDAC1HDAC2HDAC6 | |
| SCHEMBL557540 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL905423 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL11920409 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL25434198 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL905426 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL1676918 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL1510015 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL558796 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 | |
| SCHEMBL11920413 | 0.85 | EPHX2 (0.39) | HDAC1HDAC2HDAC6KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443963-B1 | ANTIBODY TARGETING COMPOUNDS | SCRIPPS RESEARCH INST (US) | 2014-05-21 | — | — | EP | disclosed |
| US-8252902-B2 | Complexing antigen, antibodies; immunoassay | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-08-28 | — | — | US | disclosed |
| EP-2428226-A1 | Antibody targeting compounds | THE SCRIPPS RESEARCH INSTITUTE (US) | 2012-03-14 | — | — | EP | disclosed |