⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536601 | 0.89 | TSHR (0.46) | — | |
| SCHEMBL15536142 | 0.88 | — | — | |
| SCHEMBL55298 | 0.84 | — | — | |
| SCHEMBL26621164 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL7736558 | 0.81 | TSHR (0.50) | — | |
| SCHEMBL4316884 | 0.80 | TSHR (0.42) | — | |
| SCHEMBL10758355 | 0.78 | TSHR (0.46) | — | |
| SCHEMBL3180403 | 0.78 | TSHR (0.46) | — | |
| SCHEMBL200253 | 0.78 | TSHR (0.46) | — | |
| SCHEMBL11136407 | 0.78 | TSHR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1893949-A | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GMBH (DE) | 2007-01-10 | — | — | CN | claimed |
| EP-2018364-B1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN INC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-7709507-B2 | Therapeutic fluoroethyl ureas | ALLERGAN, INC. (US) | 2010-05-04 | — | — | US | disclosed |
| EP-2018364-A1 | THERAPEUTIC FLUOROETHYL UREAS | Allergan, Inc. (US) | 2009-01-28 | — | — | EP | disclosed |
| WO-2007137029-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. (US) | 2007-11-29 | — | — | WO | disclosed |
| US-20070270498-A1 | THERAPEUTIC FLUOROETHYL UREAS | ALLERGAN, INC. | 2007-11-22 | — | — | US | disclosed |
| CN-1893949-A | Acidic quinoline derivatives and their use for the prevention and/or treatment of hyperglycaemia-related pathologies | MERCK PATENT GMBH (DE) | 2007-01-10 | — | — | CN | disclosed |
| US-4960884-A | Insecticides, nematocides, pesticides and miticides | FMC CORPORATION (US) | 1990-10-02 | — | — | US | disclosed |