Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 15/20 | 0.55 |
| ▸ | GRIA2 | P42262 | 10/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3391432 | 1.00 | GRIK1 (0.55) | GRIK1GRIA2ALDH1A1PDE4BMEN1 | |
| SCHEMBL3391505 | 0.91 | GRIK1 (0.45) | GRIK1GRIA2ALDH1A1MEN1KMT2A | |
| SCHEMBL3395794 | 0.88 | GRIK1 (0.57) | GRIK1GRIA2PDE4B | |
| SCHEMBL3299159 | 0.88 | GRIK1 (0.57) | GRIK1GRIA2PDE4B | |
| SCHEMBL3388752 | 0.85 | GRIK1 (0.45) | GRIK1GRIA2ALDH1A1MEN1KMT2A | |
| SCHEMBL3389093 | 0.85 | GRIK1 (0.39) | GRIK1GRIA2PDE4B | |
| SCHEMBL3303656 | 0.85 | GRIK1 (0.39) | GRIK1GRIA2PDE4B | |
| SCHEMBL3395793 | 0.85 | GRIK1 (0.41) | GRIK1GRIA2ALDH1A1P2RX3 | |
| SCHEMBL3395047 | 0.79 | GRIK1 (0.47) | GRIK1GRIA2ALDH1A1MEN1HPGD | |
| SCHEMBL3391628 | 0.78 | MEN1 (0.43) | GRIK1GRIA2ALDH1A1PDE4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | GRIK1 8/4885GRIA2 14/4885ALDH1A1 1633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.