Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F12 | P00748 | 1/20 | 1.00 |
| ▸ | PLAU | P00749 | 13/20 | 0.67 |
| ▸ | PLG | P00747 | 6/20 | 0.67 |
| ▸ | KLK1 | P06870 | 5/20 | 0.67 |
| ▸ | F2 | P00734 | 5/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.67 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | PLAT | P00750 | 4/20 | 0.51 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29568530 | 1.00 | F12 (1.00) | F12PLAUPLGKLK1F2 | |
| SCHEMBL31499215 | 1.00 | F12 (1.00) | F12PLAUPLGKLK1F2 | |
| Hydrochloric Acid SCHEMBL7837112 | 0.98 | F12 (0.96) | F12PLAUPLGKLK1F2 | |
| SCHEMBL29934139 | 0.88 | F12 (0.77) | F12PLAUPLGKLK1F2 | |
| SCHEMBL7342004 | 0.88 | F12 (0.77) | F12PLAUPLGKLK1F2 | |
| SCHEMBL29568370 | 0.88 | F12 (0.77) | F12PLAUPLGKLK1F2 | |
| SCHEMBL29941688 | 0.80 | PLAU (1.00) | F12PLAUPLGKLK1F2 | |
| SCHEMBL3370031 | 0.80 | PLAU (1.00) | F12PLAUPLGKLK1F2 | |
| SCHEMBL7362642 | 0.78 | PLAU (0.72) | F12PLAUPLGKLK1F2 | |
| SCHEMBL1808865 | 0.78 | LCK (0.70) | F12PLAUPLGF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504499-A | Synthesis method of 6-amidino-2-naphthol mesylate | 江苏杜瑞制药有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-117185963-A | Preparation method of high-purity nafamostat mesylate | 华仁药业（日照）有限公司 | 2023-12-08 | — | — | CN | claimed |
| CN-116479485-B | High-reliability lead frame and preparation method thereof | 泰州东田电子有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116479485-A | High-reliability lead frame and preparation method thereof | 泰州东田电子有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-113999145-B | Synthetic method of nafamostat mesylate | 开封明仁药业有限公司 | 2023-02-03 | — | — | CN | claimed |
| CN-113999145-A | Synthetic method of nafamostat mesylate | 开封明仁药业有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-102225903-B | Amidino guanido substituted aromatic heterocyclic copmound and synthesis and use thereof | REN JIANDONG | 2014-11-26 | — | — | CN | claimed |
| EP-0190356-B1 | NOVEL AMIDINE COMPOUNDS | TORII & CO., LTD. (JP) | 1991-03-06 | — | — | EP | claimed |
| EP-0048433-B1 | NOVEL AMIDINE COMPOUNDS, PROCESS FOR PRODUCING SAME AND ANTI-COMPLEMENT AGENT COMPRISING THEM | TORII & CO., LTD. (JP) | 1986-05-28 | — | — | EP | claimed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | claimed |
| JP-61286361-A | — | — | None | — | — | JP | disclosed |
| JP-59139357-A | — | — | None | — | — | JP | disclosed |
| JP-61022075-A | — | — | None | — | — | JP | disclosed |
| JP-57179146-A | — | — | None | — | — | JP | disclosed |
| JP-57179147-A | — | — | None | — | — | JP | disclosed |
| JP-S57179147-A | AMIDINE DERIVATIVE | TORII YAKUHIN KK | 1982-11-04 | — | — | JP | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |
| EP-0048433-A2 | Novel amidine compounds, process for producing same and anti-complement agent comprising them | TORII & CO., LTD. (JP) | 1982-03-31 | — | — | EP | disclosed |
| JP-S5753454-A | GUANIDINOBENZOATE AND ANTICOMPLEMENTARY AGENT | TORII YAKUHIN KK | 1982-03-30 | — | — | JP | disclosed |
| JP-S06122075-A | — | — | 0001-01-01 | — | — | JP | disclosed |