SCHEMBL3302120

SCHEMBL3302120

CC(Cl)(Cc1ccccc1)[Si](C)(C)Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 3/20 0.48
TAAR1 Q96RJ0 3/20 0.48
LMNA P02545 1/20 0.45
CYP2D6 P10635 1/20 0.45
TRPA1 O75762 1/20 0.40
CYP2C9 P11712 2/20 0.38
CYP2C19 P33261 2/20 0.38
CYP1A2 P05177 1/20 0.38
TP53 P04637 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAOA P21397 1/20 0.34
SLC6A4 P31645 1/20 0.34
SLC6A3 Q01959 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
AOC3 Q16853 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5091290 0.88 SLC6A2 (0.48) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL6864777 0.85 SLC6A2 (0.50) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL3528108 0.75 SLC6A2 (0.58) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL6889501 0.74 SLC6A2 (0.52) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL8398942 0.73 SLC6A2 (0.56) SLC6A2TAAR1LMNACYP2D6TRPA1
Ammonia Solution, Strong SCHEMBL28028790 0.73 SLC6A2 (0.56) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL10830666 0.71 SLC6A2 (0.67) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL10542458 0.70 SLC6A2 (0.52) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL22730168 0.69 TAAR1 (0.42) SLC6A2TAAR1LMNACYP2D6TRPA1
SCHEMBL347187 0.69 SLC6A2 (0.64) SLC6A2TAAR1LMNACYP2D6TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100093021-A1 Hardening of ordered films of silica colloids THE ARIZONA BD OF REG ON BEHALF OF THE UNIV OF AZ (US) 2010-04-15 US disclosed
US-20070254161-A1 HARDENING OF ORDERED FILMS OF SILICA COLLOIDS THE ARIZONA BD OF REG ON BEHALF OF THE UNIV OF AZ (US) 2007-11-01 US disclosed
US-7144968-B2 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED (JP) 2006-12-05 US disclosed
US-20050038216-A1 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED 2005-02-17 US disclosed
US-6709799-B2 Resist compositions SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-23 US disclosed
US-6541077-B1 Negative non-chemical amplification resist polymer or a positive chemical amplification resist polymer FUJITSU LIMITED (JP) 2003-04-01 US disclosed
US-20020120058-A1 Silicon-containing polymer, process for its production, resist composition employing it, pattern-forming method and electronic device fabrication method FUJITSU LIMITED 2002-08-29 US disclosed
US-6342562-B1 POLYSILICATE MODIFIED WITH ALKYLCARBOXY SILOXANE; AMPLIFICATION; PHOTORESIST FUJITSU LIMITED (JP) 2002-01-29 US disclosed
US-20010018161-A1 Photosensitive resin for photolithography SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-08-30 US disclosed