Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.60 |
| ▸ | PPARA | Q07869 | 20/20 | 0.60 |
| ▸ | PPARG | P37231 | 7/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RXRB | P28702 | 1/20 | 0.42 |
| ▸ | RXRG | P48443 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4113265 | 0.89 | PPARD (0.52) | PPARDPPARAPPARGNR3C1THRA | |
| SCHEMBL4127645 | 0.88 | PPARD (0.57) | PPARDPPARAPPARGNR3C1THRA | |
| SCHEMBL3307715 | 0.87 | PPARD (0.54) | PPARDPPARAPPARG | |
| SCHEMBL3307128 | 0.85 | PPARA (0.68) | PPARDPPARAPPARG | |
| SCHEMBL3306922 | 0.84 | PPARD (0.54) | PPARDPPARAPPARG | |
| SCHEMBL4122463 | 0.82 | PPARA (0.62) | PPARDPPARAPPARGNR3C1THRA | |
| SCHEMBL3306897 | 0.81 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL4112270 | 0.81 | PPARA (0.60) | PPARDPPARAPPARGNR3C1THRA | |
| SCHEMBL4125663 | 0.80 | PPARD (0.56) | PPARDPPARAPPARGNR3C1THRA | |
| SCHEMBL3303457 | 0.79 | PPARD (0.45) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.