Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 4/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3392544 | 0.83 | GRIK1 (0.46) | GRIK1GRIA2TP53LMNAMAPT | |
| SCHEMBL3300496 | 0.77 | GRIK1 (0.40) | GRIK1GRIA2TP53LMNAPOLB | |
| SCHEMBL3391198 | 0.76 | GRIK1 (0.46) | GRIK1GRIA2TP53LMNAMAPT | |
| SCHEMBL3305704 | 0.75 | GRIK1 (0.40) | GRIK1GRIA2TP53LMNAPOLB | |
| Hydrochloric Acid SCHEMBL3301966 | 0.70 | GRIK1 (0.52) | GRIK1GRIA2TP53MAPTKMT2A | |
| SCHEMBL3305703 | 0.69 | CYP3A4 (0.39) | MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL3304466 | 0.69 | CYP3A4 (0.39) | MAPTKMT2AALDH1A1KDM4E | |
| SCHEMBL3391713 | 0.69 | GRIK1 (0.35) | GRIK1GRIA2TP53MAPTPOLB | |
| SCHEMBL7066186 | 0.68 | USP30 (0.33) | LMNAKMT2AMEN1 | |
| SCHEMBL6328311 | 0.67 | NR1H2 (0.34) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | MARTINEZ-PEREZ JOSE ANTONIO | 2010-04-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100094014-A1 | EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | SLC1A2, SLC1A1, GRIN1 | GRIK1 8/4885GRIA2 14/4885TP53 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.