Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 15/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | JAK1 | P23458 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12094183 | 0.75 | DYRK1A (0.39) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL939045 | 0.72 | PIK3CG (0.54) | PIK3CGPIK3CDPIK3CBJAK2PIK3CA | |
| SCHEMBL17927920 | 0.71 | DYRK1A (0.33) | LMNA | |
| SCHEMBL12091356 | 0.71 | NAMPT (0.46) | — | |
| SCHEMBL8025930 | 0.69 | — | — | |
| SCHEMBL24656059 | 0.68 | PIK3CG (0.43) | PIK3CGPIK3CDPIK3CBPIK3CANUDT1 | |
| SCHEMBL2077769 | 0.68 | JAK2 (0.50) | PIK3CGPIK3CDPIK3CBJAK2NUDT1 | |
| SCHEMBL559382 | 0.67 | PIK3CG (0.40) | PIK3CGPIK3CDPIK3CBJAK2PIK3CA | |
| SCHEMBL21245780 | 0.67 | DYRK1A (0.42) | LMNA | |
| SCHEMBL10044580 | 0.65 | PIK3CG (0.44) | PIK3CGPIK3CDPIK3CBPIK3CANUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4041731-B1 | BICYCLIC AMINES AS CDK2 INHIBITORS | INCYTE CORP (US) | 2026-02-18 | — | — | EP | claimed |
| EP-0877745-B1 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-07-25 | — | — | EP | claimed |
| US-6005108-A | POST-EMERGENCE TOTAL VEGETATION CONTROL OR SELECTIVE CONTROL OF WEEDS IN WHEAT, RICE AND OIL-SEED RAPE CROPS | JOHNSON TIMOTHY C (US) | 1999-12-21 | — | — | US | claimed |
| WO-2025096061-A1 | CDK2 INHIBITORS AND USES THEREOF | ODYSSEY THERAPEUTICS, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2022078356-A1 | HETEROAROMATIC AHR INHIBITOR | 山东轩竹医药科技有限公司 | 2022-04-21 | — | — | WO | disclosed |
| CN-103025735-A | Process for the preparation of 5-substituted-8-alkoxy[1,2,4]triazolo[1,5-c]pyrimidin-2-amines | DOW AGROSCIENCES LLC | 2013-04-03 | — | — | CN | disclosed |
| US-8299056-B2 | Aminotriazolopyridines, compositions thereof, and methods of treatment therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2012-10-30 | — | — | US | disclosed |
| US-20100093698-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | SIGNAL PHARMACEUTICALS, LLC | 2010-04-15 | — | — | US | disclosed |
| EP-1330458-B1 | N-( 1,2,4 TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-1330458-B1 | N-( 1,2,4 TRIAZOLOAZINYL) THIOPHENESULFONAMIDE COMPOUNDS AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 2009-06-03 | — | — | EP | disclosed |
| CN-1221552-C | N- ((1,2, 4) triazoloazinyl) thiophene sulfonamide compounds as herbicides | DOW AGROSCIENCES LLC (US) | 2005-10-05 | — | — | CN | disclosed |
| EP-0877745-A2 | N-( 1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | Dow Agrosciences LLC (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1998013367-A1 | N-([1,2,4] TRIAZOLOAZINYL)BENZENESULFONAMIDE AND PYRIDINESULFONAMIDE COMPOUNDS AND THEIR USE AS HERBICIDES | DOW AGROSCIENCES LLC (US) | 1998-04-02 | — | — | WO | disclosed |
| EP-0121341-B1 | TRIAZOLO(4,3-C)PYRIMIDINES AND TRIAZOLO(1,5-C)PYRIMIDINES SUBSTITUTED BY NITROGEN-CONTAINING HETEROCYCLIC RINGS | RIKER LABORATORIES, INCORPORATED (US) | 1988-11-17 | — | — | EP | disclosed |
| EP-0269774-A1 | Metabolites of triazolo[1,5-c]pyridines | RIKER LABORATORIES, INCORPORATED (US) | 1988-06-08 | — | — | EP | disclosed |
| US-4639445-A | BRONCHODILATORS | RIKER LABORATORIES (US) | 1987-01-27 | — | — | US | disclosed |
| US-4591588-A | Triazolo[1,5-c]pyrimidines and bronchodilation use thereof | RIKER LABORATORIES, INC. (US) | 1986-05-27 | — | — | US | disclosed |
| US-4572910-A | BRONCHODILATORS | RIKER LABORATORIES, INC. (US) | 1986-02-25 | — | — | US | disclosed |
| US-4528288-A | Substituted triazolo[1,5-c]pyrimidines | RIKER LABORATORIES, INC. (US) | 1985-07-09 | — | — | US | disclosed |
| EP-0121341-A1 | Triazolo(4,3-c)pyrimidines and triazolo(1,5-c)pyrimidines substituted by nitrogen-containing heterocyclic rings | RIKER LABORATORIES, INCORPORATED (US) | 1984-10-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093698-A1 | AMINOTRIAZOLOPYRIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH | MAP3K2, MAP3K1, MAP3K3 | PIK3CG 776/4885PIK3CD 510/4885PIK3CB 513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.