Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.41 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | FBP1 | P09467 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3311532 | 0.83 | PPARD (0.39) | PPARDPPARAFBP1PPARGPTGDR2 | |
| SCHEMBL3310471 | 0.80 | PPARD (0.36) | PPARDPPARAFBP1PPARG | |
| SCHEMBL3303462 | 0.80 | PPARD (0.36) | PPARDPPARAFBP1PPARG | |
| SCHEMBL5861831 | 0.74 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL4791916 | 0.74 | KDM4E (0.41) | PPARDPPARAFBP1PPARG | |
| SCHEMBL4831903 | 0.74 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL3306901 | 0.72 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL3306529 | 0.71 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL13899140 | 0.71 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL13899142 | 0.71 | PPARD (0.43) | PPARDPPARAFBP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY | 2010-04-22 | — | — | US | disclosed |
| EP-2129667-A2 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2009-12-09 | — | — | EP | disclosed |
| WO-2008103574-A2 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2008-08-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885FBP1 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.