Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 20/20 | 0.44 |
| ▸ | PPARA | Q07869 | 20/20 | 0.44 |
| ▸ | PPARG | P37231 | 16/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3306945 | 0.90 | PPARA (0.44) | PPARDPPARAPPARG | |
| SCHEMBL3306901 | 0.85 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL3302122 | 0.84 | PPARD (0.43) | PPARDPPARAPPARG | |
| SCHEMBL3303946 | 0.82 | PPARA (0.51) | PPARDPPARAPPARG | |
| SCHEMBL3307717 | 0.81 | PPARA (0.44) | PPARDPPARAPPARG | |
| SCHEMBL3306926 | 0.81 | PPARD (0.44) | PPARDPPARAPPARG | |
| SCHEMBL3311532 | 0.77 | PPARD (0.39) | PPARDPPARAPPARG | |
| SCHEMBL3965143 | 0.74 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL3964614 | 0.74 | PPARD (0.46) | PPARDPPARAPPARG | |
| SCHEMBL3310471 | 0.73 | PPARD (0.36) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099725-A1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | PPARA, PPARG, PPARD | PPARD 3/4885PPARA 1/4885PPARG 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.