⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2464 | 0.83 | — | — | |
| SCHEMBL7899584 | 0.77 | — | — | |
| SCHEMBL28475574 | 0.77 | — | — | |
| SCHEMBL28818354 | 0.77 | — | — | |
| SCHEMBL2496478 | 0.77 | — | — | |
| SCHEMBL23343 | 0.77 | — | — | |
| SCHEMBL477908 | 0.74 | — | — | |
| SCHEMBL10125 | 0.74 | — | — | |
| SCHEMBL23874 | 0.72 | — | — | |
| SCHEMBL6061107 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 360 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973164-B2 | Quinoline derivatives | ASTRAZENECA AB (SE) | 2011-07-05 | — | — | US | claimed |
| US-20090233950-A1 | QUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-09-17 | — | — | US | claimed |
| US-20090076075-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | claimed |
| US-20090076074-A1 | QUINOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2009-03-19 | — | — | US | claimed |
| US-20090042910-A1 | QUINOLINE DERIVATIVES FOR TREATING CANCER | ASTRAZENECA AB (SE) | 2009-02-12 | — | — | US | claimed |
| US-20090036485-A1 | Quinoline derivatives | JUNG FREDERIC HENRI | 2009-02-05 | — | — | US | claimed |
| EP-1994023-A1 | QUINAZOLINE DERIVATIVES | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | claimed |
| EP-1994024-A2 | QUINOLINE DERIVATIVES | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | claimed |
| EP-1994028-A1 | QUINOLINE DERIVATIVES FOR TREATING CANCER | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | claimed |
| EP-1994025-A1 | QUINOLINE DERIVATIVES | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | claimed |
| US-20020165231-A1 | Substituted N-heteroaryl-N-phenyl aminoalcohol compounds useful for inhibiting cholesteryl ester transfer protein activity | SIKORSKI JAMES A (US) | 2002-11-07 | — | — | US | claimed |
| CN-1328464-A | Use of phosphonoformic acid derivatives for treating infections | JOMMA PHARMACEUTICAL AG (DE) | 2001-12-26 | — | — | CN | claimed |
| CN-1328465-A | Use of phosphonoformic acid derivatives for treating infections | JOMAA PHARMACEUTICAL AG (DE) | 2001-12-26 | — | — | CN | claimed |
| EP-0799238-A2 | 14ALPHA,17ALPHA-C2-BRIDGED 19-NOR-PROGESTERONE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-10-08 | — | — | EP | claimed |
| WO-1996020209-A2 | 14α,17α-C2-BRIDGED 19-NOR-PROGESTERONE DERIVATIVES | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-07-04 | — | — | WO | claimed |
| EP-0421102-B1 | Substituted acrylic acid esters | BAYER AG (DE) | 1995-03-29 | — | — | EP | claimed |
| EP-0421102-A2 | Substituted acrylic acid esters | BAYER AG (DE) | 1991-04-10 | — | — | EP | claimed |
| EP-0094146-B1 | ANTIFUNGAL AZOLYL PHENYL SUBSTITUTED ALICYCLIC ALCOHOLS | ZENECA LIMITED (GB) | 1987-01-14 | — | — | EP | claimed |
| US-4503062-A | PLANT FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-05 | — | — | US | claimed |
| EP-0094146-A1 | Antifungal azolyl phenyl substituted alicyclic alcohols | ZENECA LIMITED (GB) | 1983-11-16 | — | — | EP | claimed |