Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.36 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308611 | 1.00 | TSHR (0.39) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL28102522 | 0.83 | HMGCR (0.40) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL28071097 | 0.83 | HMGCR (0.40) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL29627131 | 0.77 | FASN (0.45) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL27697824 | 0.77 | FASN (0.45) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL28070993 | 0.77 | FASN (0.45) | TSHRALDH1A1HMGCRFASNFAAH | |
| SCHEMBL28070991 | 0.77 | HMGCR (0.58) | HMGCRFASNFAAHKDM4E | |
| SCHEMBL23727076 | 0.75 | FASN (0.56) | HMGCRFASNFAAHKDM4E | |
| SCHEMBL6473565 | 0.75 | — | — | |
| SCHEMBL6479729 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100098788-A1 | Extracts of Curcuma and Methods of Use Thereof | HERBALSCIENCE GROUP, LLC | 2010-04-22 | — | — | US | disclosed |