Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | SREBF1 | P36956 | 1/20 | 0.72 |
| ▸ | VDR | P11473 | 7/20 | 0.62 |
| ▸ | PGR | P06401 | 2/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.62 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | GC | P02774 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 1/20 | 0.62 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.62 |
| ▸ | CNR1 | P21554 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | HTR2C | P28335 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.62 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.62 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16136801 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL16136800 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL13301764 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL3312401 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL13556501 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL13301837 | 1.00 | MAPT (0.72) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL3330143 | 0.95 | MAPT (0.71) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL13301771 | 0.95 | MAPT (0.71) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL3330139 | 0.95 | MAPT (0.71) | MAPTSMN1; SMN2SREBF1VDRPGR | |
| SCHEMBL13301765 | 0.95 | MAPT (0.64) | MAPTSMN1; SMN2SREBF1VDRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10258635-B2 | Formulations and compositions of vitamin D analogs for treating and preventing cancer and other diseases | APHIOS CORPORATION (US) | 2019-04-16 | — | — | US | disclosed |
| US-20160184329-A1 | Formulations and Compositions of Vitamin D Analogs for Treating and Preventing Cancer and other Diseases | APHIOS CORP (US) | 2016-06-30 | — | — | US | disclosed |
| US-20100113378-A1 | Compositions and Methods for Treating and Preventing Cancer Using Analogs of Vitamin D | RAY RAHUL | 2010-05-06 | — | — | US | disclosed |
| US-20080317870-A1 | Compositions and Mehtods for Treating and Preventing Cancer Using Analogs of Vitamin D | RAY RAHUL | 2008-12-25 | — | — | US | disclosed |
| US-20050059641-A1 | Compositions and methods for treating and preventing cancer using analogs of vitamin D | APHIOS CORPORATION | 2005-03-17 | — | — | US | disclosed |