Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.54 |
| ▸ | HRH1 | P35367 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308511 | 0.99 | MEN1 (0.55) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3310391 | 0.98 | KMT2A (0.60) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3309315 | 0.97 | MEN1 (0.58) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3313103 | 0.95 | MEN1 (0.55) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3315917 | 0.93 | HRH3 (0.49) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3308883 | 0.91 | HRH3 (0.56) | KMT2AMEN1HRH3HRH1KCNH2 | |
| SCHEMBL3306714 | 0.91 | HRH3 (0.56) | KMT2AMEN1HRH3HRH1KCNH2 | |
| SCHEMBL3314509 | 0.91 | KMT2A (0.51) | KMT2AMEN1HRH3HRH1ALDH1A1 | |
| SCHEMBL3308265 | 0.89 | HRH3 (0.56) | KMT2AMEN1HRH3HRH1KCNH2 | |
| SCHEMBL3310831 | 0.88 | HRH3 (0.47) | KMT2AMEN1HRH3HRH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2010-05-06 | — | — | US | claimed |
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | TAISHO PHARMACEUTICAL CO.,LTD. (JP) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113776-A1 | PYRAZOLE DERIVATIVE | HRH3, HRH4, HRH1 | KMT2A 340/4885MEN1 3118/4885HRH3 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.