Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1824001 | 1.00 | MAPT (0.47) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL29097448 | 1.00 | MAPT (0.47) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL1824002 | 1.00 | MAPT (0.47) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL5004973 | 1.00 | MAPT (0.47) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL9137960 | 0.86 | MAPT (0.55) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL11073044 | 0.86 | MAPT (0.55) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL8512702 | 0.86 | MAPT (0.55) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL8512700 | 0.86 | MAPT (0.55) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL4962623 | 0.85 | MAPT (0.52) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL652994 | 0.85 | MAPT (0.52) | MAPTALDH1A1POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288500-A1 | Methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-B-D-arabinofuranosyl)-9H-purin-6-amine | SOUTHERN RESEARCH INSTITUTE (US) | 2005-12-29 | — | — | US | claimed |
| US-6949640-B2 | Method for synthesizing 2-chloro-9-(2-fluoro-β-D-arabinofuranosyl)-9H-purin-6-amine | SOUTHERN RESEARCH INSTITUTE (US) | 2005-09-27 | — | — | US | claimed |
| EP-1261350-A4 | METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-$g(b)-D-ARABINOFURANOSYL)- i 9H /i -PURIN-6-AMINE | SOUTHERN RES INST (US) | 2003-04-16 | — | — | EP | claimed |
| US-20030023078-A1 | Method for synthesizing 2-chloro-9-(2-fluoro-beta-d-arabinofuranosyl)-9h-purin-6-amine | SOUTHERN RESEARCH INSTITUTE | 2003-01-30 | — | — | US | claimed |
| EP-1261350-A1 | METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-$g(b)-D-ARABINOFURANOSYL)- i 9H /i -PURIN-6-AMINE | Southern Research Institute (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2001060383-A1 | METHODS FOR SYNTHESIZING 2-CHLORO-9-(2-DEOXY-2-FLUORO-β-D-ARABINOFURANOSYL)-9H-PURIN-6-AMINE | SOUTHERN RESEARCH INSTITUTE (US) | 2001-08-23 | — | — | WO | claimed |
| EP-0428109-A2 | Deoxyfluoronucleoside process | Bristol-Myers Squibb Company (US) | 1991-05-22 | — | — | EP | claimed |
| US-8394935-B2 | Method for producing furanose derivative | API CORPORATION (JP) | 2013-03-12 | — | — | US | disclosed |
| US-20100105890-A1 | METHOD FOR PRODUCING FURANOSE DERIVATIVE | API CORPORATION (JP) | 2010-04-29 | — | — | US | disclosed |
| EP-2105445-A1 | METHOD FOR PRODUCTION OF FURANOSE DERIVATIVE | API Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105890-A1 | METHOD FOR PRODUCING FURANOSE DERIVATIVE | DERA, ALDOA, DPYD | MAPT 4811/4885ALDH1A1 127/4885POLB 2130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.