⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL881429 | 0.86 | — | — | |
| SCHEMBL3318734 | 0.86 | — | — | |
| SCHEMBL25294321 | 0.83 | TSHR (0.36) | — | |
| SCHEMBL1780853 | 0.83 | — | — | |
| SCHEMBL13939240 | 0.79 | GAA (0.31) | — | |
| SCHEMBL18232561 | 0.78 | — | — | |
| SCHEMBL12380783 | 0.75 | — | — | |
| SCHEMBL18232563 | 0.74 | — | — | |
| Nitrous Acid SCHEMBL597561 | 0.73 | TSHR (0.34) | — | |
| SCHEMBL23586974 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11897891-B2 | Tricyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2024-02-13 | — | — | US | claimed |
| CN-116730972-A | Crown ether supermolecular compound with phase change characteristic and preparation method thereof | 东南大学 | 2023-09-12 | — | — | CN | claimed |
| WO-2021159993-A1 | INHIBITORS OF INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE (IRAK) /FMS-LIKE RECEPTOR TYROSINE KINASE (FLT3), PHARMACEUTICAL PRODUCTS THEREOF, AND METHODS THEREOF | PHARMABLOCK SCIENCES (NANJING) , INC. (CN) | 2021-08-19 | — | — | WO | claimed |
| WO-2021113479-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2021-06-10 | — | — | WO | claimed |
| US-20210171535-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2021-06-10 | — | — | US | claimed |
| CN-110085879-A | A kind of Co9S8/ sulphur nitrogen is co-doped with carbon composite and preparation method thereof | 中国科学院山西煤炭化学研究所 | 2019-08-02 | — | — | CN | claimed |
| CN-105837584-B | The imidazole radicals imidazoles of condensation as antiviral compound | 吉利德制药有限责任公司 | 2018-07-13 | — | — | CN | claimed |
| CN-106432254-A | Antiviral compounds inhibitors of HVC NS5B | 吉利德制药有限责任公司 | 2017-02-22 | — | — | CN | claimed |
| CN-105837584-A | Condensed imidazolylimidazoles as antiviral compounds | 吉利德制药有限责任公司 | 2016-08-10 | — | — | CN | claimed |
| CN-103328480-A | Condensed imidazolylimidazoles as antiviral compounds | GILEAD SCIENCES INC | 2013-09-25 | — | — | CN | claimed |
| US-20030050246-A1 | Peptides having antiangiogenic activity | ABBOTT LABORATORIES | 2003-03-13 | — | — | US | claimed |
| US-20030045477-A1 | Peptides having antiangiogenic activity | ABBOTT LABORATORIES | 2003-03-06 | — | — | US | claimed |
| WO-2003011896-A1 | PEPTIDES HAVING ANTIANGIOGENIC ACTIVITY | ABBOTT LABORATORIES (US) | 2003-02-13 | — | — | WO | claimed |
| CN-1347412-A | aryloxy dithiazole dioxides | BAYER AG (DE) | 2002-05-01 | — | — | CN | claimed |
| CN-1220663-A | Substituted phenyl uracils | BAYER AG (DE) | 1999-06-23 | — | — | CN | claimed |
| US-5719280-A | REACTING AMINE SUBSTITUTED BENZOCYCLOALKANE WITH DIALKYLOXYACETALDEHYDE IN PRESENCE OF REDUCING AGENT OR CATALYTIC HYDROGENATION, TREATING WITH THIOCYANIC ACID | SYNTEX (U.S.A.) INC. (US) | 1998-02-17 | — | — | US | claimed |
| CN-1151735-A | Benzocycloalkylazolethione derivatives | SYNTEX INC (US) | 1997-06-11 | — | — | CN | claimed |
| EP-0757677-A1 | BENZOCYCLOALKYLAZOLETHIONE DERIVATIVES | SYNTEX (U.S.A.) INC. (US) | 1997-02-12 | — | — | EP | claimed |
| US-5538988-A | CARDIOVASCULAR DISORDERS AND DOPAMINE HYDROLASE ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. | 1996-07-23 | — | — | US | claimed |
| WO-1995029165-A2 | BENZOCYCLOALKYLAZ0LETHIONE DERIVATIVES AS DOPAMIN BETA-HYDROXYLASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1995-11-02 | — | — | WO | claimed |