Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 10/20 | 0.48 |
| ▸ | PPARA | Q07869 | 11/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3298881 | 0.98 | PPARG (0.46) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3370847 | 0.95 | PPARG (0.45) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL13295227 | 0.94 | KDM4E (0.48) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3371224 | 0.93 | PPARG (0.43) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3297799 | 0.92 | PPARA (0.46) | PPARGPPARATP53PPARDCYP2C9 | |
| SCHEMBL13114657 | 0.92 | KDM4E (0.48) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3297707 | 0.90 | PPARA (0.46) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3292476 | 0.88 | PPARG (0.46) | PPARGPPARATP53PPARDMAPT | |
| SCHEMBL3292431 | 0.88 | PPARG (0.41) | PPARGPPARATP53PPARDKDM4E | |
| SCHEMBL3292836 | 0.88 | PPARA (0.43) | PPARGPPARATP53PPARDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902039-B1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI AVENTIS (FR) | 2010-10-13 | — | — | EP | disclosed |
| EP-1902039-B1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI AVENTIS (FR) | 2010-10-13 | — | — | EP | disclosed |
| US-7732471-B2 | 6-oxazol-4-ylmetholmethoxy-alko-alkoxymethyl substituted benzoic acid derivatives forming peroxisome proliferator—activated receptor (PPAR) ligands, process for their preparation and methods of use thereof | SANOFI-AVENTIS (FR) | 2010-06-08 | — | — | US | disclosed |
| US-7732471-B2 | 6-oxazol-4-ylmetholmethoxy-alko-alkoxymethyl substituted benzoic acid derivatives forming peroxisome proliferator—activated receptor (PPAR) ligands, process for their preparation and methods of use thereof | SANOFI-AVENTIS (FR) | 2010-06-08 | — | — | US | disclosed |
| US-7732471-B2 | 6-oxazol-4-ylmetholmethoxy-alko-alkoxymethyl substituted benzoic acid derivatives forming peroxisome proliferator—activated receptor (PPAR) ligands, process for their preparation and methods of use thereof | SANOFI-AVENTIS (FR) | 2010-06-08 | — | — | US | disclosed |
| US-20080171776-A1 | 6-OXAZOL-4-YLMETHOLMETHOXY-ALKO-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PEROXISOME PROLIFERATOR - ACTIVATED RECEPTOR (PPAR) LIGANDS, PROCESS FOR THEIR PREPARATION AND METHODS OF USE THEREOF | SANOFI-AVENTIS (FR) | 2008-07-17 | — | — | US | disclosed |
| US-20080171776-A1 | 6-OXAZOL-4-YLMETHOLMETHOXY-ALKO-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PEROXISOME PROLIFERATOR - ACTIVATED RECEPTOR (PPAR) LIGANDS, PROCESS FOR THEIR PREPARATION AND METHODS OF USE THEREOF | SANOFI-AVENTIS (FR) | 2008-07-17 | — | — | US | disclosed |
| US-20080171776-A1 | 6-OXAZOL-4-YLMETHOLMETHOXY-ALKO-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PEROXISOME PROLIFERATOR - ACTIVATED RECEPTOR (PPAR) LIGANDS, PROCESS FOR THEIR PREPARATION AND METHODS OF USE THEREOF | SANOFI-AVENTIS (FR) | 2008-07-17 | — | — | US | disclosed |
| EP-1902039-A1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | Sanofi-Aventis (FR) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007000235-A1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | disclosed |
| WO-2007000235-A1 | 6-OXAZOL-4-YLMETHOXY-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PPAR LIGANDS, METHODS FOR PRODUCTION AND THE USE THEREOF IN THE FORM OF DRUGS | SANOFI-AVENTIS (DE) | 2007-01-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171776-A1 | 6-OXAZOL-4-YLMETHOLMETHOXY-ALKO-ALKOXYMETHYL SUBSTITUTED BENZOIC ACID DERIVATIVES FORMING PEROXISOME PROLIFERATOR - ACTIVATED RECEPTOR (PPAR) LIGANDS, PROCESS FOR THEIR PREPARATION AND METHODS OF USE THEREOF | PPARA, PPARG, PPARD | PPARG 2/4885PPARA 1/4885TP53 2862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.