Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD74 | P04233 | 1/20 | 0.79 |
| ▸ | MIF | P14174 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 13/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 13/20 | 0.75 |
| ▸ | NPC1 | O15118 | 13/20 | 0.75 |
| ▸ | RAB9A | P51151 | 11/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.74 |
| ▸ | POLB | P06746 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 2/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.66 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | ECE2 | P0DPD6 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319480 | 1.00 | CD74 (0.79) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL6428720 | 0.98 | CD74 (0.77) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL28200632 | 0.98 | CD74 (0.77) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL8344151 | 0.89 | CD74 (1.00) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL28473985 | 0.87 | CD74 (0.75) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL28473988 | 0.87 | CD74 (0.75) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL3854732 | 0.83 | MEN1 (0.77) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL7691066 | 0.82 | MEN1 (0.76) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL29084196 | 0.82 | CD74 (0.72) | CD74MIFMEN1KMT2ANPC1 | |
| SCHEMBL7691068 | 0.82 | MEN1 (0.76) | CD74MIFMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9255686-A | — | — | None | — | — | JP | disclosed |
| US-20100105144-A1 | ONIUM SALTS AND USE THEREOF FOR DETECTING AND ASSAYING METALS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-04-29 | — | — | US | disclosed |
| US-20100105144-A1 | ONIUM SALTS AND USE THEREOF FOR DETECTING AND ASSAYING METALS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-04-29 | — | — | US | disclosed |
| US-20100105144-A1 | ONIUM SALTS AND USE THEREOF FOR DETECTING AND ASSAYING METALS | COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) | 2010-04-29 | — | — | US | disclosed |
| EP-2112138-A1 | Onium salts and their use for detecting and dosing metals | Commissariat a L'Energie Atomique (FR) | 2009-10-28 | — | — | EP | disclosed |
| US-6500842-B1 | N-((4-CHLOROPHENYL)METHYL)-8-HYDROXY-7-QUINOLINECARBOXAMIDE ADMINISTERED AS VIRICIDES AGAINST HERPES VIRUS | PHARMACIA & UPJOHN COMPANY | 2002-12-31 | — | — | US | disclosed |
| US-6310211-B1 | ANTI-VIRAL ACTIVITY AGAINST HERPES VIRUS, CYTOMEGALOVIRUS. MANY OF THESE COMPOUNDS ARE ALSO ACTIVE AGAINST VARICELLA ZOSTER VIRUS, EPSTEIN-BARR VIRUS, HERPES SIMPLEX VIRUS AND HUMAN HERPES VIRUS TYPE 8 | PHARMACIA & UPJOHN COMPANY | 2001-10-30 | — | — | US | disclosed |
| US-6252080-B1 | HERPES, CYTOMEGALO VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-06-26 | — | — | US | disclosed |
| US-6211376-B1 | HERPES VIRUS, CYTOMEGALO VIRUS, VARICELLA-ZOSTER VIRUS,EPSTEIN-BARR VIRUS | PHARMACIA & UPJOHN COMPANY | 2001-04-03 | — | — | US | disclosed |
| EP-0927164-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1999-07-07 | — | — | EP | disclosed |
| WO-1998011073-A1 | 8-HYDROXY-7-SUBSTITUTED QUINOLINES AS ANTI-VIRAL AGENTS | PHARMACIA & UPJOHN COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| JP-H09255686-A | STYRYL-8-HYDROXY-QUINOLINES AND PRODUCTION OF THE SAME | KEMIPURO KASEI KK | 1997-09-30 | — | — | JP | disclosed |
| US-5445916-A | Photopolymers based on polyvinyl alcohol derivatives of 8-hydroxyquinoline compositions | ULANO CORPORATION (US) | 1995-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105144-A1 | ONIUM SALTS AND USE THEREOF FOR DETECTING AND ASSAYING METALS | SLC30A7, SLC30A5, AS3MT | CD74 1635/4885MIF 3290/4885MEN1 1565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.