SCHEMBL331908

SCHEMBL331908

COC(=O)C1(N)CCCC1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.50
CYP4F2 P78329 1/20 0.41
CYP4A11 Q02928 1/20 0.41
MAPT P10636 1/20 0.38
CYP3A4 P08684 2/20 0.37
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
TSHR P16473 2/20 0.36
CYP2C19 P33261 1/20 0.36
LMNA P02545 2/20 0.35
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240008 0.98 NPSR1 (0.48) NPSR1CYP4F2CYP4A11MAPTCYP3A4
SCHEMBL1772581 0.98 NPSR1 (0.48) NPSR1CYP4F2CYP4A11MAPTCYP3A4
Hydrochloric Acid SCHEMBL485571 0.98 NPSR1 (0.48) NPSR1CYP4F2CYP4A11MAPTCYP3A4
SCHEMBL28766822 0.98 NPSR1 (0.48) NPSR1CYP4F2CYP4A11MAPTCYP3A4
SCHEMBL1809800 0.98 NPSR1 (0.48) NPSR1CYP4F2CYP4A11MAPTCYP3A4
Hydrochloric Acid SCHEMBL5196791 0.95 NPSR1 (0.47) NPSR1CYP4F2CYP4A11MAPTCYP3A4
Hydrochloric Acid SCHEMBL1115400 0.95 NPSR1 (0.47) NPSR1CYP4F2CYP4A11MAPTCYP3A4
Hydrochloric Acid SCHEMBL1809798 0.95 NPSR1 (0.47) NPSR1CYP4F2CYP4A11MAPTCYP3A4
Hydrochloric Acid SCHEMBL644319 0.95 NPSR1 (0.47) NPSR1CYP4F2CYP4A11MAPTCYP3A4
SCHEMBL1433032 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 261 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP claimed
CN-118164897-A Spirotemporal compound and preparation method and application thereof 南开大学 2024-06-11 CN claimed
CN-117886737-A Spiroteine framework compound and preparation method and application thereof 安徽农业大学 2024-04-16 CN claimed
CN-115417790-A Novel azo foaming agent and synthesis method thereof 山东大学 2022-12-02 CN claimed
US-20200317615-A1 PALLADIUM (II)-CATALYZED gammaC(SP3)-H ALKYNYLATION OF AMINE2 COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2020-10-08 US claimed
US-10787418-B1 Palladium (II)-catalyzed γC(SP3)-H alkynylation of amines COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2020-09-29 US claimed
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists DOMAIN THERAPEUTICS (FR) 2026-01-20 US disclosed
EP-3967714-B1 VINYL ALCOHOL-AMINO ACID ESTER COPOLYMER, THEIR PREPARATION AND USES SEKISUI CHEMICAL CO LTD (JP) 2026-01-07 EP disclosed
US-12435165-B2 Vinyl alcohol-amino acid ester copolymer SEKISUI CHEMICAL CO., LTD. (JP) 2025-10-07 US disclosed
CN-119080976-A Vinyl alcohol-amino acid ester copolymer 积水化学工业株式会社 2024-12-06 CN disclosed
CN-118164897-B Spirotemporal compound and preparation method and application thereof 南开大学 2024-11-15 CN disclosed
EP-3240542-B1 BTK INHIBITORS MERCK SHARP & DOHME LLC (US) 2024-11-06 EP disclosed
CN-113795520-B Vinyl alcohol-amino acid ester copolymer 积水化学工业株式会社 2024-08-30 CN disclosed
US-5663297-A OLIGOPEPTIDES HOFFMANN-LA ROCHE INC. (US) 1997-09-02 US disclosed
US-5512681-A HORMONE INHIBITORS FOR TREATMENT OF HYPERTENSION OR CONGESTIVE HEART FAILURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-04-30 US disclosed
EP-0601039-A1 ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-06-15 EP disclosed
EP-0249434-B1 Peptide derivatives and processes for their preparation VYZK USTAV FARM BIOCHEM SP (CZ) 1994-05-04 EP disclosed
US-4898930-A Peptide derivatives and processes for their preparation SPOFA, SPOJENE PODNIKY PRO (CS) 1990-02-06 US disclosed
EP-0249434-A2 Peptide derivatives and processes for their preparation Vyzkumny ustav pro farmacii a biochemii (CZ) 1987-12-16 EP disclosed
US-4610817-A N-acyl derivatives of peptides, their preparation and their use in the treatment of disorders, and agents for this purpose BASF AKTIENGESELLSCHAFT (DE) 1986-09-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12527779-B2 Prostaglandin E2 (PGE2) EP4 receptor antagonists PTGER1, PTGER4, PTGER3 NPSR1 670/4885CYP4F2 1433/4885CYP4A11 552/4885
US-20200317615-A1 PALLADIUM (II)-CATALYZED gammaC(SP3)-H ALKYNYLATION OF AMINE2 POLE3, BUB3, POLR2H NPSR1 743/4885CYP4F2 3214/4885CYP4A11 4058/4885
US-10787418-B1 Palladium (II)-catalyzed γC(SP3)-H alkynylation of amines POLE3, BUB3, POLR2H NPSR1 433/4885CYP4F2 3757/4885CYP4A11 3881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.