Nerol

Nerol

SCHEMBL3319949

CC(C)=CCC/C(C)=C\CO.CC(C)=CCC/C(C)=C\CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 1.00
MEN1 O00255 2/20 1.00
CYP3A4 P08684 2/20 1.00
ALOX15 P16050 2/20 1.00
MAPT P10636 2/20 0.95
ALDH1A1 P00352 2/20 0.95
UGT1A1 P22309 1/20 0.95
SQLE Q14534 7/20 0.67
KDM4E B2RXH2 2/20 0.56
ICMT O60725 1/20 0.53
ATM Q13315 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nerol SCHEMBL19825 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL2874022 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL30529087 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL8676054 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL19824 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL11280775 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL9051249 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL118988 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL21173796 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT
Geraniol SCHEMBL19826 1.00 KMT2A (1.00) KMT2AMEN1CYP3A4ALOX15MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11612575-B2 Combination therapies with disulfiram Spring Discovery, Inc. (US) 2023-03-28 US disclosed
US-20220087956-A1 COMBINATION THERAPIES WITH DISULFIRAM WINTER ACQUISITION SUB, INC. 2022-03-24 US disclosed
US-11065214-B1 Combination therapies with disulfiram Spring Discovery, Inc. (US) 2021-07-20 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
US-11033516-B1 Combination therapies with disulfiram Spring Discovery, Inc. (US) 2021-06-15 US disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
EP-3365418-A2 PARTICLES FOR MALODOR REDUCTION The Procter and Gamble Company (US) 2018-08-29 EP disclosed
EP-3197510-A1 DELIVERY SYSTEMS COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter & Gamble Company (US) 2017-08-02 EP disclosed
EP-3197422-A1 CLEANING AND/OR TREATMENT COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS The Procter & Gamble Company (US) 2017-08-02 EP disclosed
EP-3197426-A1 FRESHENING COMPOSITIONS AND DEVICES COMPRISING SAME THE PROCTER & GAMBLE COMPANY (US) 2017-08-02 EP disclosed
WO-2016049389-A1 MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO disclosed
WO-2016049455-A1 PERSONAL CARE COMPOSITIONS COMPRISING MALODOR REDUCTION COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2016-03-31 WO disclosed
US-8580728-B2 Use of fragrance compositions for the prevention of the development of indole base malodours from fecal and urine based soils TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-11-12 US disclosed
EP-1884251-B1 Use of fragrance compositions for restricting the formation of indole from faecal and urine based soils TAKASAGO PERFUMERY CO LTD (JP) 2013-08-28 EP disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
US-20100104525-A1 USE OF FRAGRANCE COMPOSITIONS FOR THE PREVENTION OF THE DEVELOPMENT OF INDOLE BASE MALODOURS FROM FECAL AND URINE BASED SOILS TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-04-29 US disclosed
US-20080032912-A1 Use of fragrance compositions for the prevention of the development of indole base malodours from fecal and urine based soils TAKASAGO INTERNATIONAL CORPORATION (JP) 2008-02-07 US disclosed
EP-1884251-A1 Use of fragrance compositions for the prevention of the development of indole based malodours from faecal and urine based soils Takasago International Corporation (JP) 2008-02-06 EP disclosed
US-5716928-A ADMINISTERING DRUG CONCURRENTLY WITH ESSENTIAL OIL AVMAX, INC. (US) 1998-02-10 US disclosed
US-5665386-A Use of essential oils to increase bioavailability of oral pharmaceutical compounds AVMAX, INC. (US) 1997-09-09 US disclosed