Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL7117953 | 0.98 | CA4 (0.31) | CA4 | |
| Ethylenediamine SCHEMBL8037427 | 0.98 | CA4 (0.31) | CA4 | |
| Ammonia Solution, Strong SCHEMBL9155073 | 0.77 | CA4 (0.32) | CA4 | |
| SCHEMBL7164695 | 0.75 | CA4 (0.33) | CA4 | |
| SCHEMBL9561685 | 0.74 | CA4 (0.35) | CA4 | |
| SCHEMBL10704360 | 0.74 | CA4 (0.36) | CA4 | |
| Ammonia Solution, Strong SCHEMBL7519046 | 0.72 | CA4 (0.48) | CA4 | |
| Potassium Ion SCHEMBL9421273 | 0.71 | CA12 (0.31) | — | |
| SCHEMBL8958617 | 0.71 | CA4 (0.33) | CA4 | |
| Ethylenediamine SCHEMBL15352445 | 0.71 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120916-A1 | THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES | SBI ALAPROMO CO., LTD. (JP) | 2010-05-13 | — | — | US | claimed |
| EP-2135613-A1 | REMEDY AND DIAGNOSTIC FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASE | SBI ALApromo CO., LTD. (JP) | 2009-12-23 | — | — | EP | claimed |
| EP-3281642-B1 | DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES | SBI PHARMACEUTICALS CO LTD (JP) | 2019-05-01 | — | — | EP | disclosed |
| EP-3281642-A1 | DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES | SBI Pharmaceuticals Co., Ltd. (JP) | 2018-02-14 | — | — | EP | disclosed |
| US-20100120916-A1 | THERAPEUTIC AGENT AND DIAGNOSTIC AGENT FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASES | SBI ALAPROMO CO., LTD. (JP) | 2010-05-13 | — | — | US | disclosed |
| EP-2135613-A1 | REMEDY AND DIAGNOSTIC FOR MITOCHONDRIAL DYSFUNCTION BRAIN DISEASE | SBI ALApromo CO., LTD. (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-0395442-A2 | Stabilizer for silver halide photographic light-sensitive material use and the method of processing the light-sensitive material with the stabilizer | KONICA CORPORATION (JP) | 1990-10-31 | — | — | EP | disclosed |