Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Ceftiofur. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | NR1I2 | O75469 | 6/20 | 0.70 |
| ▸ | HTR2C | P28335 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | PPARG | P37231 | 2/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.68 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | PGR | P06401 | 3/20 | 0.67 |
| ▸ | DAO | P14920 | 1/20 | 0.65 |
| ▸ | SNCA | P37840 | 1/20 | 0.65 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | APEX1 | P27695 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ceftiofur SCHEMBL30278638 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL10296647 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL30278637 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL12727853 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL332042 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL13330460 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL16072838 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL9367220 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL6155826 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG | |
| Ceftiofur SCHEMBL4729007 | 1.00 | KMT2A (1.00) | KMT2ANR1I2HTR2CMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 7594 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12637481-B2 | Boronic acid derivatives and therapeutic uses thereof | QPEX BIOPHARMA, INC. (US) | 2026-05-26 | — | — | US | claimed |
| US-12629336-B2 | Compositions and methods of use thereof for treatment of mastitis | CUREMAST, INC. (US) | 2026-05-19 | — | — | US | claimed |
| US-12564612-B2 | Microbial strains and antibiotics | MICROBIAL DISCOVERY GROUP, LLC (US) | 2026-03-03 | — | — | US | claimed |
| US-12502264-B2 | Injection apparatus and method for use | phi-Tech Animal Health Technologies (IL) | 2025-12-23 | — | — | US | claimed |
| WO-2025224119-A1 | METHOD OF ENRICHING A CELL POPULATION CONTAINING INTACT AND DAMAGED CELLS IN A LIQUID MEDIUM | TrophoSYS GmbH (DE) | 2025-10-30 | — | — | WO | claimed |
| US-12371429-B2 | Antibiotic resistance-modifying tricyclic heteroaryl compounds and uses thereof | RECREO PHARMACEUTICALS LLC (US) | 2025-07-29 | — | — | US | claimed |
| US-20250222118-A1 | Beta-Lactam-Cannabinoid Conjugate Molecules | DIVERSE BIOTECH INC (US) | 2025-07-10 | — | — | US | claimed |
| EP-4552693-A2 | COLLAGEN PEPTIDE-BASED MEDICAMENT COMPOSITIONS AND DEVICES AND METHODS OF PRODUCTION AND USE THEREOF | Sustain Holdings, LLC (US) | 2025-05-14 | — | — | EP | claimed |
| CN-119909058-A | Application of naringenin nano-particles in preparation of ceftiofur long-acting preparation | 通威农业发展有限公司 | 2025-05-02 | — | — | CN | claimed |
| CN-119842544-A | Lactobacillus rhamnosus and application thereof | 塔里木大学 | 2025-04-18 | — | — | CN | claimed |
| EP-0180372-B1 | CRYSTALLINE CEPHALOSPORIN ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1992-01-08 | — | — | EP | claimed |
| US-5079007-A | Mixture of amorphous and crystalline cephalosporin | THE UPJOHN COMPANY (US) | 1992-01-07 | — | — | US | claimed |
| EP-0393150-A1 | ZINC CEFTIOFUR COMPLEXES | THE UPJOHN COMPANY (US) | 1990-10-24 | — | — | EP | claimed |
| EP-0386000-A1 | CONTROLLED RELEASE OF ANTIBIOTIC SALTS FROM AN IMPLANT. | UPJOHN CO (US) | 1990-09-12 | — | — | EP | claimed |
| US-4877782-A | ANTIBIOTICS | THE UPJOHN COMPANY (US) | 1989-10-31 | — | — | US | claimed |
| WO-1989007600-A1 | ZINC CEFTIOFUR COMPLEXES | THE UPJOHN COMPANY (US) | 1989-08-24 | — | — | WO | claimed |
| EP-0329286-A1 | Zinc ceftiofur complexes | THE UPJOHN COMPANY (US) | 1989-08-23 | — | — | EP | claimed |
| WO-1989000852-A1 | CONTROLLED RELEASE OF ANTIBIOTIC SALTS FROM AN IMPLANT | THE UPJOHN COMPANY (US) | 1989-02-09 | — | — | WO | claimed |
| EP-0233255-A1 | CONVERSION OF CEPHALOSPORIN HYDROHALIDE SALT TO ALKALI METAL SALT. | UPJOHN CO (US) | 1987-08-26 | — | — | EP | claimed |
| WO-1987001117-A2 | CONVERSION OF CEPHALOSPORIN HYDROHALIDE SALT TO ALKALI METAL SALT | THE UPJOHN COMPANY (US) | 1987-02-26 | — | — | WO | claimed |