SCHEMBL33223

SCHEMBL33223

C/C=C\I

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL173213 1.00
SCHEMBL881085 1.00
SCHEMBL67375 0.72
SCHEMBL8280790 0.71
SCHEMBL17994017 0.71
SCHEMBL15839638 0.71
SCHEMBL7634996 0.71
SCHEMBL12344999 0.69
SCHEMBL12344948 0.69
SCHEMBL21806852 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178432-A Novel preparation method of fosfomycin sodium 鼎元(天津)生物医药科技有限公司 2023-05-30 CN claimed
CN-116178432-A Novel preparation method of fosfomycin sodium 鼎元(天津)生物医药科技有限公司 2023-05-30 CN disclosed
US-20180215748-A1 EPOTHILONE B AND DICTYOSTATIN ANALOGS, THEIR PREPARATION AND USE THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2018-08-02 US disclosed
US-20170227553-A1 COMPOSITIONS AND METHODS FOR IDENTIFYING AND TREATING CONDITIONS INVOLVING HSF1 ACTIVITY NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2017-08-10 US disclosed
WO-2017103604-A1 HYDANTOIN MODULATORS OF KV3 CHANNELS AUTIFONY THERAPEUTICS LIMITED (GB) 2017-06-22 WO disclosed
US-20170107175-A1 Crystalline Diacylhydrazine and the Use Thereof INTREXON CORPORATION (US) 2017-04-20 US disclosed
US-20170088620-A1 ASGR INHIBITORS AMGEN INC 2017-03-30 US disclosed
US-9605049-B2 Chimeric receptors with 4-1BB stimulatory signaling domain ST. JUDE CHILDREN'S RESEARCH HOSPITAL, INC. (US) 2017-03-28 US disclosed
EP-2078003-B1 ANILINOPIPERAZINE DERIVATIVES AND METHODS OF USE THEREOF MERCK SHARP & DOHME (US) 2017-03-08 EP disclosed
US-9499660-B2 Silicon-based cross coupling agents and methods of their use THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2016-11-22 US disclosed
US-20100022600-A1 METHODS AND COMPOSITIONS FOR TREATING CENTRAL NERVOUS SYSTEM TUMORS LANDRETH GARY E 2010-01-28 US disclosed
US-20100022749-A1 Contoxin Analogues and Methods for Synthesizing Same MONASH UNIVERSITY (AU) 2010-01-28 US disclosed
US-20090270717-A1 APPARATUS AND METHOD FOR DIAGNOSIS OF OPTICALLY IDENTIFIABLE OPHTHALMIC CONDITIONS WELCH ALLYN, INC. (US) 2009-10-29 US disclosed
US-7538190-B2 Methods for the synthesis of two or more dicarba bridges in organic compounds POLYCHIP PHARMACEUTICALS PTY LTD (AU) 2009-05-26 US disclosed
WO-2009053108-A1 A DYE INCLUDING AN ANCHORING GROUP IN ITS MOLECULAR STRUCTURE SONY CORPORATION (JP) 2009-04-30 WO disclosed
US-7507384-B2 Preferential oxidation reactor temperature regulation NUVERA FUEL CELLS, INC. (US) 2009-03-24 US disclosed
US-20080288228-A1 BIOLOGICAL SIMULATION SYSTEM AND COMPUTER PROGRAM PRODUCT SYSMEX CORPORATION 2008-11-20 US disclosed
US-20080255400-A1 Hydrotalcite-Like Substance, Process for Producing the Same and Method of Immobilizing Hazardous Substance WASEDA UNIVERSITY (JP) 2008-10-16 US disclosed
US-7326540-B2 Methods for identifying compounds that modulate stabilization of secretase-associated proteins THE GENERAL HOSPITAL CORPORATION (US) 2008-02-05 US disclosed
US-7156358-B2 Interior rearview mirror assembly with polymeric components DONNELLY CORPORATION (US) 2007-01-02 US disclosed