Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 3/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24654499 | 0.96 | CHRM2 (0.37) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL26969191 | 0.94 | CHRM2 (0.43) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL10937659 | 0.92 | CHRM2 (0.43) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL6967400 | 0.89 | — | — | |
| SCHEMBL3186493 | 0.86 | HRH3 (0.42) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| Hydrochloric Acid SCHEMBL27567168 | 0.84 | HRH4 (0.41) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| Hydrochloric Acid SCHEMBL6897821 | 0.84 | HRH4 (0.41) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL24951938 | 0.84 | HRH4 (0.39) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL20095943 | 0.83 | HRH3 (0.40) | HRH4HRH3SIGMAR1ABCB11ADORA3 | |
| SCHEMBL6961851 | 0.82 | CHRM2 (0.48) | SIGMAR1ADH1AADH1CKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0080817-B1 | A PROCESS FOR REMOVING ACID GASES USING A BASIC SALT ACTIVATED WITH A NON-STERICALLY HINDERED DIAMINO COMPOUND | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1985-07-10 | — | — | EP | claimed |
| US-4376101-A | Process for removing acid gases using a basic salt activated with a non-sterically hindered diamine | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-03-08 | — | — | US | claimed |
| CN-118459351-A | Synthesis method of multifunctional N- (aminopropyl) amine compound | 榆林中科洁净能源创新研究院 | 2024-08-09 | — | — | CN | disclosed |
| CN-116874742-A | Curable epoxy resin composition and preparation method and application thereof | 万华化学集团股份有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-9957263-B2 | Bromodomain inhibitors | ABBVIE INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160272630-A1 | Bromodomain Inhibitors | ABBVIE INC. (US) | 2016-09-22 | — | — | US | disclosed |
| EP-3013827-A1 | BROMODOMAIN INHIBITORS | AbbVie Inc. (US) | 2016-05-04 | — | — | EP | disclosed |
| EP-2139472-B1 | TETRAHYDROINDOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2016-01-13 | — | — | EP | disclosed |
| WO-2014206345-A1 | BROMODOMAIN INHIBITORS | ABBVIE INC. (US) | 2014-12-31 | — | — | WO | disclosed |
| US-8288432-B2 | Tetrahydroindole derivatives as NADPH oxidase inhibitors | GENKYOTEX SA (CH) | 2012-10-16 | — | — | US | disclosed |
| US-7807704-B2 | Bicyclic, nitrogen-containing compounds modulating CXCR4 and/or CCXCKR2 | CHEMOCENTRYX, INC. (US) | 2010-10-05 | — | — | US | disclosed |
| US-4525589-A | Isoquinolinesulfonyl derivatives | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-06-25 | — | — | US | disclosed |
| EP-0061673-B1 | ISOQUINOLINESULFONYL DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-24 | — | — | EP | disclosed |
| US-4456757-A | MUSCLE RELAXANTS, VASODILATORS, HYPOTENSIVE AGENTS | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1984-06-26 | — | — | US | disclosed |
| EP-0080817-A1 | A process for removing acid gases using a basic salt activated with a non-sterically hindered diamino compound | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
| US-4376101-A | Process for removing acid gases using a basic salt activated with a non-sterically hindered diamine | EXXON RESEARCH AND ENGINEERING CO. (US) | 1983-03-08 | — | — | US | disclosed |
| EP-0061673-A1 | Isoquinolinesulfonyl derivatives and process for the preparation thereof | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1982-10-06 | — | — | EP | disclosed |
| US-4104276-A | BASIC COPPER PHTHALOCYANINES, CRYSTALLIZATION | BASF AKTIENGESELLSCHAFT (DE) | 1978-08-01 | — | — | US | disclosed |
| US-4069064-A | Phthalocyanine formulations having high gloss, which are stabilized against recrystallization and against change of modification | BASF AKTIENGESELLSCHAFT (DT) | 1978-01-17 | — | — | US | disclosed |
| US-4039346-A | Conversion of crude copper phthalocyanines into pigments | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272630-A1 | Bromodomain Inhibitors | BRD4, BRDT, EP300 | HRH4 2270/4885HRH3 1490/4885SIGMAR1 3409/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.