Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3327428 | 0.91 | PDE2A (0.67) | PDE2APDE10A | |
| SCHEMBL3324228 | 0.83 | PDE2A (0.60) | PDE2APDE10A | |
| SCHEMBL3325218 | 0.79 | PDE2A (0.63) | PDE2APDE10A | |
| SCHEMBL3325849 | 0.79 | PDE2A (0.66) | PDE2APDE10A | |
| SCHEMBL3325981 | 0.78 | PDE2A (0.75) | PDE2APDE10A | |
| SCHEMBL3330434 | 0.78 | PDE2A (0.69) | PDE2APDE10A | |
| SCHEMBL3324433 | 0.77 | PDE2A (0.62) | PDE2APDE10A | |
| SCHEMBL3322157 | 0.77 | PDE2A (0.72) | PDE2APDE10A | |
| SCHEMBL3327353 | 0.76 | PDE2A (0.70) | PDE2APDE10A | |
| SCHEMBL14054227 | 0.76 | PDE2A (1.00) | PDE2APDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120763-A1 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | WYETH (US) | 2010-05-13 | — | — | US | claimed |
| US-20100120763-A1 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | WYETH (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120763-A1 | IMIDAZO[5,1-C][1,2,4]BENZOTRIAZINE DERIVATIVES AS INHIBITORS OF PHOSPHODIESTERASES | PDE2A, PDE5A, PDE3A | PDE2A 1/4885PDE10A 13/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.