Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Albuterol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 9/20 | 0.87 |
| ▸ | PMP22 | Q01453 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.87 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.87 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.87 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.87 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.85 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | CASP1 | P29466 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Albuterol SCHEMBL3635442 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL33280 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL29372778 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Levosalbutamol SCHEMBL29568212 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL6861017 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Levosalbutamol SCHEMBL33281 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL2405201 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL2556890 | 1.00 | PMP22 (1.00) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL15995296 | 0.99 | PMP22 (0.97) | PMP22ADRB2HIF1AADRB1CYP1A2 | |
| Albuterol SCHEMBL5472402 | 0.99 | PMP22 (0.97) | PMP22ADRB2HIF1AADRB1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 20877 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122071418-A | Preparation method of salbutamol sulfate, salbutamol sulfate injection and preparation method of salbutamol sulfate injection | 海南皇隆制药股份有限公司 | 2026-05-22 | — | — | CN | claimed |
| US-20260139860-A1 | PRODUCTS OF MANUFACTURE FOR THE TREATMENT, PREVENTION AND AMELIORATION OF MICROBIAL INFECTIONS | CENTRE FOR DIGESTIVE DISEASES (AU) | 2026-05-21 | — | — | US | claimed |
| EP-4743371-A1 | DEVICE FOR DISPENSING A FLUID PRODUCT | APTAR France SAS (FR) | 2026-05-20 | — | — | EP | claimed |
| EP-4739600-A1 | DEVICE FOR DISPENSING A FLUID PRODUCT | APTAR France SAS (FR) | 2026-05-13 | — | — | EP | claimed |
| EP-4739295-A1 | AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA | Norton (Waterford) Limited (IE) | 2026-05-13 | — | — | EP | claimed |
| EP-4739294-A1 | AN INHALABLE FORMULATION OF FLUTICASONE PROPIONATE AND ALBUTEROL SULFATE FOR THE TREATMENT OF ASTHMA | Norton (Waterford) Limited (IE) | 2026-05-13 | — | — | EP | claimed |
| US-20260090584-A1 | SYSTEMS AND METHODS FOR ESTIMATING AEROSOLIZATION EMISSION | SCIENTIFIC HORIZONS CONSULTING LLC (US) | 2026-04-02 | — | — | US | claimed |
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| EP-4110442-B1 | INHALER | KINDEVA DRUG DELIVERY LP (US) | 2026-02-11 | — | — | EP | claimed |
| US-12545948-B2 | Identification of novel loci in asthma and methods of use thereof for the diagnosis and treatment of asthma | THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) | 2026-02-10 | — | — | US | claimed |
| WO-1992000062-A1 | THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-01-09 | — | — | WO | claimed |
| EP-0223671-B1 | MEDICAMENT WITH A SYNERGISTIC ANTI-INFLAMMATORY EFFECT ON THE BASIS OF A CORTICOSTEROID AND A BETA-AGONIST | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1991-11-27 | — | — | EP | claimed |
| EP-0455463-A1 | Packaging for microdoses of powdered medicament for inhalation | RIKER LABORATORIES, INC. (US) | 1991-11-06 | — | — | EP | claimed |
| WO-1991014422-A1 | THE USE OF SOLUBLE FLUOROSURFACTANTS FOR THE PREPARATION OF METERED-DOSE AEROSOL FORMULATIONS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1991-10-03 | — | — | WO | claimed |
| EP-0369608-A1 | Gel bases for pharmaceutical compositions | THAMES PHARMACAL CO.INC. (US) | 1990-05-23 | — | — | EP | claimed |
| EP-0351897-A2 | Skin penetration system for salts of amine-functional drugs | THE PROCTER & GAMBLE COMPANY (US) | 1990-01-24 | — | — | EP | claimed |
| US-4883660-A | Gel bases for pharmaceutical compositions | THAMES PHARMACAL CO., INC. (US) | 1989-11-28 | — | — | US | claimed |
| EP-0223671-A1 | Medicament with a synergistic anti-inflammatory effect on the basis of a corticosteroid and a beta-agonist | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES GALDERMA - CIRD GALDERMA (FR) | 1987-05-27 | — | — | EP | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4499108-A | BRONCHODILATER, ADRENERGIC BLOCKING AGENT | SCHERING CORPORATION (US) | 1985-02-12 | — | — | US | claimed |