Pivalate

Pivalate

SCHEMBL332912

CC(C)(C)C(=O)O.CC(C)(C)C(=O)O

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.61
ALDH1A1 P00352 3/20 0.61
CYP2D6 P10635 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44
TP53 P04637 1/20 0.43
FFAR3 O14843 2/20 0.42
LCK P06239 1/20 0.42
FYN P06241 1/20 0.42
HMGCR P04035 1/20 0.39
CHRM1 P11229 1/20 0.39
TBXA2R P21731 1/20 0.39
ADRA1A P35348 1/20 0.39
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
TET2 Q6N021 1/20 0.35
MAPT P10636 1/20 0.33
PTGS1 P23219 1/20 0.33
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pivalate SCHEMBL5116637 1.00 TSHR (0.61) TSHRALDH1A1CYP2D6CYP2C19HIF1A
Pivalate SCHEMBL3613 1.00
Pivalate SCHEMBL4318862 1.00
Pivalate SCHEMBL15771206 0.95
Pivalate SCHEMBL6516524 0.95
Pivalate SCHEMBL25209317 0.95
Pivalate SCHEMBL5274713 0.95 TSHR (0.57) TSHRALDH1A1CYP2D6CYP2C19HIF1A
Pivalate SCHEMBL10822159 0.95
Pivalate SCHEMBL1685641 0.95
Pivalate SCHEMBL6113208 0.95

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023279473-A1 ANTI-FOG EASILY-REMOVED COATING FILM AND PREPARATION METHOD THEREFOR 海南赛诺实业有限公司 2023-01-12 WO claimed
EP-1820793-B1 Process of stabilization of nucleic acids in biological materials QIAGEN GMBH (DE) 2011-09-14 EP claimed
US-7977402-B2 Photocation polymerization initiator, a free-radical photoinitiator; an acrylate ester of a carboxylic acid ester; and material containing a radiation curable functional group; imppulse printheads COLLINS INK CORPORATION (US) 2011-07-12 US claimed
EP-0269696-B1 TRANSDERMAL ABSORPTION DOSAGE UNIT FOR ESTRADIOL AND OTHER ESTROGENIC STEROIDS UNIV RUTGERS (US) 1994-08-03 EP claimed
EP-0075189-B1 3-BETA,7-BETA,15-ALPHA-TRIHYDROXY-5-ANDROSTEN-17-ONE, ITS 3,15-DIPIVALATE, AND ITS PREPARATION SCHERING AKTIENGESELLSCHAFT (DE) 1985-08-28 EP claimed
US-4435327-A 3β,7β,15α-Trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and their preparation SCHERING, AKTIENGESELLSCHAFT (DE) 1984-03-06 US claimed
EP-0075189-A1 3-Beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation SCHERING AKTIENGESELLSCHAFT (DE) 1983-03-30 EP claimed
WO-2023279473-A1 ANTI-FOG EASILY-REMOVED COATING FILM AND PREPARATION METHOD THEREFOR 海南赛诺实业有限公司 2023-01-12 WO disclosed
CN-114096542-A Condensed tricyclic pyrroles as alpha-1 antitrypsin modulators 弗特克斯药品有限公司 2022-02-25 CN disclosed
WO-2021215852-A1 PHARMACEUTICAL COMPOSITION FOR TREATMENT OF HYPERTROPHIC CARDIOMYOPATHY AND TREATMENT METHOD USING SAME COMPOSITION (주)셀트리온 (KR) 2021-10-28 WO disclosed
CN-105733048-B Vulcanized nitrile rubber composition and preparation method thereof 中国石油天然气股份有限公司 2017-10-17 CN disclosed
CN-105733048-A Vulcanized nitrile rubber composition and preparation method thereof 中国石油天然气股份有限公司 2016-07-06 CN disclosed
CN-104936582-A Compositions and methods for transdermal delivery of hormones and other medicinal agents TEIKOKU PHARMA USA INC 2015-09-23 CN disclosed
CN-1036211-A The continuous processing of handling with cycling stream prepares high impact polystyrene FINA TECHNOLOGY (US) 1989-10-11 CN disclosed
EP-0075189-B1 3-BETA,7-BETA,15-ALPHA-TRIHYDROXY-5-ANDROSTEN-17-ONE, ITS 3,15-DIPIVALATE, AND ITS PREPARATION SCHERING AKTIENGESELLSCHAFT (DE) 1985-08-28 EP disclosed
US-4435327-A 3β,7β,15α-Trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and their preparation SCHERING, AKTIENGESELLSCHAFT (DE) 1984-03-06 US disclosed
US-4435327-A 3β,7β,15α-Trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and their preparation SCHERING, AKTIENGESELLSCHAFT (DE) 1984-03-06 US disclosed
EP-0075189-A1 3-Beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation SCHERING AKTIENGESELLSCHAFT (DE) 1983-03-30 EP disclosed
EP-0075189-A1 3-Beta,7-beta,15-alpha-trihydroxy-5-androsten-17-one, its 3,15-dipivalate, and its preparation SCHERING AKTIENGESELLSCHAFT (DE) 1983-03-30 EP disclosed
EP-0047339-A1 Drug for the local treatment of glaucoma Dr. Thilo & Co. GmbH (DE) 1982-03-17 EP disclosed