Formamide

Formamide

SCHEMBL3330461

CNC(C)(O)N(C)C.NC=O

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formamide SCHEMBL3632800 0.98
SCHEMBL770079 0.84
Ammonia Solution, Strong SCHEMBL2635295 0.82
Formamide SCHEMBL16648441 0.74 TSHR (0.30)
Trimethylammonium SCHEMBL27422984 0.62
Dimethylamine SCHEMBL6456619 0.62
Methylhydrazine SCHEMBL28606267 0.59
Formamide SCHEMBL20721941 0.59
Formamide SCHEMBL28155924 0.59
Tert-Butanol SCHEMBL9717203 0.58 TSHR (0.64)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10100002-B2 Method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether from a mixture HUNTSMAN INTERNATIONAL LLC (US) 2018-10-16 US disclosed
EP-3057937-A1 METHOD FOR SEPARATING N,N,N'-TRIMETHYLBISAMINOETHYLETHER AND/OR N,N-DIMETHYLBISAMINOETHYLETHER FROM A MIXTURE Huntsman Corporation Hungary ZRt. (HU) 2016-08-24 EP disclosed
US-20160237024-A1 Method for Separating N,N,N'-Trimethylbisaminoethylether and/or N,N-Dimethylbisaminoethylether from a Mixture Huntsman Corporation Hungary ZRt (HU) 2016-08-18 US disclosed
WO-2015055406-A1 METHOD FOR SEPARATING N,N,N'-TRIMETHYLBISAMINOETHYLETHER AND/OR N,N-DIMETHYLBISAMINOETHYLETHER FROM A MIXTURE HUNTSMAN CORPORATION HUNGARY ZRT. (HU) 2015-04-23 WO disclosed
EP-2862851-A1 Method for separating N,N,N'-trimethylbisaminoethylether and/or N,N-dimethylbisaminoethylether from a mixture Huntsman Corporation Hungary ZRt. (HU) 2015-04-22 EP disclosed
EP-2148742-B1 SEPARATION OF N,N,N'-TRIMETHYLBISAMINOETHYLETHER FROM MIXTURES COMPRISING TERTIARY AMINES OR TERTIARY AMINOALKYLETHERS HUNTSMAN INT LLC (US) 2014-04-16 EP disclosed
US-8232223-B2 Separation of N,N,N′-trimethylbisamino-ethylether from mixtures comprising tertiary amines or tertiary aminoalkylethers HUNTSMAN INTERNATIONAL LLC (US) 2012-07-31 US disclosed
US-20100144517-A1 Separation from catalyst precursor N,N,N',N'-tetramethylbisaminoethyl ether via transamidation; azeotropic composition comprising N,N,N'-trimethylbisaminoethylether and monoethanolamine HUNTSMAN INTERNATIONAL LLC. (US) 2010-06-10 US disclosed
EP-2148742-A2 SEPARATION OF N,N,N'-TRIMETHYLBISAMINOETHYLETHER FROM MIXTURES COMPRISING TERTIARY AMINES OR TERTIARY AMINOALKYLETHERS Huntsman International LLC (US) 2010-02-03 EP disclosed
WO-2008140957-A2 SEPARATION OF N,N,N'-TRIMETHYLBISAMINOETHYLETHER FROM MIXTURES COMPRISING TERTIARY AMINES OR TERTIARY AMINOALKYLETHRS HUNTSMAN INTERNATIONAL LLC (US) 2008-11-20 WO disclosed