SCHEMBL333104

SCHEMBL333104

c1cn(-c2ncc[nH]2)cn1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.41
LMNA P02545 2/20 0.38
MAPT P10636 1/20 0.38
ENPP2 Q13822 1/20 0.38
MKNK1 Q9BUB5 1/20 0.38
MKNK2 Q9HBH9 1/20 0.38
NOTUM Q6P988 1/20 0.38
CYP19A1 P11511 3/20 0.37
CYP2A6 P11509 1/20 0.37
HIPK2 Q9H2X6 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
IDO1 P14902 2/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
LOXL2 Q9Y4K0 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2D6 P10635 3/20 0.35
CYP2C9 P11712 3/20 0.35
CYP2C19 P33261 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9013312 0.93 CYP3A4 (0.36) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL114028 0.78 HIPK2 (0.41) HIPK2MEN1KMT2AALOX15
SCHEMBL1916742 0.68 CYP3A4 (0.38) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL27827547 0.68 IDO1 (0.49) CYP3A4LMNAMAPTCYP19A1MEN1
SCHEMBL8128240 0.67 CYP3A4 (0.37) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL16923117 0.66 CYP3A4 (0.54) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL10919818 0.65 CYP2A6 (0.39) LMNACYP2A6HIPK2CYP1A2CYP2D6
SCHEMBL9464563 0.65 CYP3A4 (0.39) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL27607780 0.65 CYP3A4 (0.48) CYP3A4LMNAMAPTENPP2MKNK1
SCHEMBL989991 0.64 CYP3A4 (0.52) CYP3A4LMNAMAPTENPP2MKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 87 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111116483-B 2-imidazolyl imidazole compound and preparation method thereof 浙江师范大学 2022-12-20 CN claimed
CN-111116483-A 2-imidazolyl imidazole compound and preparation method thereof 浙江师范大学 2020-05-08 CN claimed
CN-107573443-A For 3D printing technique by visible light-initiated photoinitiator composite and application 宁波七诺新材料科技有限公司 2018-01-12 CN claimed
CN-116555165-B Cervical cancer organoid culture medium and application thereof 重庆大学附属肿瘤医院 2024-08-06 CN disclosed
CN-116555165-A Cervical cancer organoid culture medium and application thereof 重庆大学附属肿瘤医院 2023-08-08 CN disclosed
US-11567410-B2 Pattern formation method, laminate, and method of producing touch panel FUJIFILM CORPORATION (JP) 2023-01-31 US disclosed
CN-111116483-B 2-imidazolyl imidazole compound and preparation method thereof 浙江师范大学 2022-12-20 CN disclosed
CN-111116483-B 2-imidazolyl imidazole compound and preparation method thereof 浙江师范大学 2022-12-20 CN disclosed
CN-111116483-B 2-imidazolyl imidazole compound and preparation method thereof 浙江师范大学 2022-12-20 CN disclosed
CN-115433207-A Macrocyclic heterocyclic compound as EGFR inhibitor and application thereof 南京圣和药业股份有限公司 2022-12-06 CN disclosed
CN-114409725-A Oleanolic acid A ring derivative with anti-tumor activity and preparation method thereof 沈阳化工大学 2022-04-29 CN disclosed
WO-2003072614-A2 THIOL COMPOUND, PHOTOPOLYMERIZATION INITIATOR COMPOSITION AND PHOTOSENSITIVE COMPOSITION SHOWA DENKO K.K. (JP) 2003-09-04 WO disclosed
US-6413686-B2 MIXTURE OF VOLATILITY AND NONVOLATILITY COMPONENTS; IMPURITIES EXTRACTION DAI NIPPON PRINTING CO., LTD. (JP) 2002-07-02 US disclosed
EP-1033626-A1 Radiation sensitive composition JSR Corporation (JP) 2000-09-06 EP disclosed
US-6051368-A A MIXTURE COMPRISING AN ORGANIC POLYMER BINDER OF A CELLULOSE ETHER AND AN ALKALI-SOLUBLE RESIN, A PHOTO-CROSSLINKABLE COMPOUND AND A PHOTO-RADICAL GENERATING AGENT; FORMING A FLUORESCENT SCREEN, SIDE SURFACES OF A PLASMA DISPLAY PANEL JSR CORPORATION (JP) 2000-04-18 US disclosed
EP-0513397-B1 BENZOHYDROXIMOYLAZOLE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-04-14 EP disclosed
US-5366988-A Insecticides or aphidicides KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1994-11-22 US disclosed
US-5246914-A Fungicides and plant growth regulators BASF AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed
US-5227304-A Imidazole buffer, microbiocide, isotonic solution SEQUOIA TURNER CORPORATION (US) 1993-07-13 US disclosed
EP-0513397-A1 BENZOHYDROXIMOYLAZOLE DERIVATIVE, PRODUCTION THEREOF AND INSECTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1992-11-19 EP disclosed