Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Calcifediol Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR known ✓ | P11473 | 8/20 | 0.82 |
| ▸ | MAPT | P10636 | 5/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | SREBF1 | P36956 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 3/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.82 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.82 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.82 |
| ▸ | PGR | P06401 | 2/20 | 0.82 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.82 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.82 |
| ▸ | CDC25A | P30304 | 1/20 | 0.82 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.82 |
| ▸ | HPGD | P15428 | 1/20 | 0.82 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.82 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.82 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.82 |
| ▸ | DRD3 | P35462 | 1/20 | 0.82 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Calcifediol Anhydrous SCHEMBL10018928 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL13301741 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL9933434 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL3296 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL24102681 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL5614025 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL24051907 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL14112503 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL24571935 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 | |
| Calcifediol Anhydrous SCHEMBL22403256 | 1.00 | MAPT (1.00) | MAPTSMN1; SMN2SREBF1VDRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 731 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122084348-A | Neutral dissociating agent for detecting 25-hydroxy vitamin D content in human blood sample and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-122084707-A | 25-Hydroxy vitamin D3Molecularly imprinted electrochemical sensor, preparation method and application thereof | — | 2026-05-26 | — | — | CN | claimed |
| CN-224241579-U | 25-Hydroxy vitamin D detection kit | 合肥谱佳医学检验实验室有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-121569886-A | Additive composition and application thereof | 凯恩格生物科技(宜昌)有限公司 | 2026-02-27 | — | — | CN | claimed |
| CN-120154576-A | Child dosage forms, methods of manufacture and use | 欧普科爱尔兰环球控股有限公司 | 2025-06-17 | — | — | CN | claimed |
| CN-115575649-B | 25-Hydroxy vitamin D dissociating agent and preparation method and application thereof | 无锡百泰克生物技术有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120121593-A | 25-Hydroxy vitamin D dissociating agent and preparation method and application thereof | 广州万孚生物技术股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120077126-A | Oxidation of steroids | 牛津大学创新有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120058583-A | Quality control product or calibrator of 25-hydroxy vitamin D and related application thereof | 瑞莱谱(杭州)医疗科技有限公司 | 2025-05-30 | — | — | CN | claimed |
| WO-2025094144-A1 | CONTROLLING LOSS OF KIDNEY FUNCTION | EIRGEN PHARMA LTD. (IE) | 2025-05-08 | — | — | WO | claimed |
| CN-115112810-A | Sample pretreatment method for 25-hydroxy vitamin D detection and application | 山西尚宁高科技医学检验中心(有限公司) | 2022-09-27 | — | — | CN | claimed |
| CN-115097148-A | 25 hydroxy vitamin D detect reagent box | 山东博科生物产业有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-104523707-B | Oral controlled release compositions comprising vitamin D compounds and waxy carriers | 欧普科IP 控股II 有限公司 | 2022-08-26 | — | — | CN | claimed |
| US-20220211077-A1 | COMBINATION OF 25-HYDROXYVITAMIN D AND ANTIOXIDANTS/ANTI-INFLAMMATORIES FOR POULTRY OVARIAN HEALTH | DSM IP ASSETS BV (NL) | 2022-07-07 | — | — | US | claimed |
| CN-114609261-A | Method for detecting 25-hydroxy vitamin D in dry blood spots by using HPLC-MS (high Performance liquid chromatography-Mass Spectrometry) in combination | 中科南京生命健康高等研究院 | 2022-06-10 | — | — | CN | claimed |
| CN-112129956-B | Colloidal gold labeling solution for colloidal gold immunochromatography, and preparation method and application thereof | 武汉生之源生物科技股份有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-114527269-A | Device for continuously testing multiple human body physiological indexes | 棒糖科技(杭州)股份有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-114441678-A | Detection method and detection kit for high-stability 25-hydroxyvitamin D | 苏州药明泽康生物科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| CN-114280177-A | Detection method of fat-soluble vitamin A, D, E | 上海市徐汇区中心医院 | 2022-04-05 | — | — | CN | claimed |
| CN-113884687-B | Dissociation agent for detecting content of 25-hydroxy vitamin D and preparation method thereof | 南京岚轩生物科技有限公司 | 2022-02-11 | — | — | CN | claimed |