Calcifediol Anhydrous

Calcifediol Anhydrous

SCHEMBL3333460

C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)CCCC(C)(C)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

VDR

The experimentally established mechanism targets of Calcifediol Anhydrous. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VDR known ✓ P11473 8/20 0.82
MAPT P10636 5/20 1.00
SMN1; SMN2 Q16637 3/20 1.00
SREBF1 P36956 1/20 1.00
MEN1 O00255 3/20 0.82
KMT2A Q03164 3/20 0.82
ALDH1A1 P00352 2/20 0.82
CYP3A4 P08684 2/20 0.82
ALOX15 P16050 2/20 0.82
PGR P06401 2/20 0.82
ADORA3 P0DMS8 2/20 0.82
TDP1 Q9NUW8 1/20 0.82
CDC25A P30304 1/20 0.82
HSPD1 P10809 1/20 0.82
HPGD P15428 1/20 0.82
TBXA2R P21731 1/20 0.82
PTGS1 P23219 1/20 0.82
GLRA1 P23415 1/20 0.82
DRD3 P35462 1/20 0.82
HSPE1 P61604 1/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Calcifediol Anhydrous SCHEMBL10018928 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL13301741 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL9933434 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL3296 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL24102681 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL5614025 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL24051907 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL14112503 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL24571935 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1
Calcifediol Anhydrous SCHEMBL22403256 1.00 MAPT (1.00) MAPTSMN1; SMN2SREBF1VDRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3152185-B1 METHOD AND USAGE OF A SALT FOR SEPARATING EPIMERS BY ION MOBILITY SPECTROMETRY ROCHE DIAGNOSTICS GMBH (DE) 2023-10-04 EP claimed
EP-3805224-B1 ANALYSIS METHOD OF DIENE COMPOUND AND PRODUCTION METHOD OF ENE COMPOUND JEOL LTD (JP) 2023-04-12 EP claimed
EP-4623289-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST F. Hoffmann-La Roche AG (CH) 2025-10-01 EP disclosed
US-12272440-B2 Methods, systems, and apparatus for optimizing effects of treatment with medication using medication compliance patterns I.D. THERAPEUTICS LLC (US) 2025-04-08 US disclosed
EP-4437338-A1 METHOD FOR DETERMINING AN ANALYTE OF INTEREST BY FREQUENCY DETECTION F. Hoffmann-La Roche AG (CH) 2024-10-02 EP disclosed
CN-111983244-B Detection method and detection kit for four vitamins in dried blood spots 天津国科医疗科技发展有限公司 2024-10-01 CN disclosed
US-20240249821-A1 METHODS, SYSTEMS, AND APPARATUS FOR OPTIMIZING EFFECTS OF TREATMENT WITH MEDICATION USING MEDICATION COMPLIANCE PATTERNS I.D. THERAPEUTICS LLC (US) 2024-07-25 US disclosed
WO-2024110422-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST F. HOFFMANN-LA ROCHE AG (CH) 2024-05-30 WO disclosed
CN-118090988-A Method for detecting total amount of 25-hydroxy vitamin D in breast milk 北京三元食品股份有限公司 2024-05-28 CN disclosed
US-11942209-B2 Methods, systems, and apparatus for optimizing effects of treatment with medication using medication compliance patterns I.D. THERAPEUTICS LLC (US) 2024-03-26 US disclosed
US-20230420240-A1 AUTOMATED CLINICAL DIAGNOSTIC SYSTEM AND METHOD ROCHE DIAGNOSTICS OPERATIONS, INC. 2023-12-28 US disclosed
EP-4154009-A1 REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2023-03-29 EP disclosed
EP-4153572-A1 IMIDAZOLIUM REAGENT FOR MASS SPECTROMETRY F. Hoffmann-La Roche AG (CH) 2023-03-29 EP disclosed
WO-2022136286-A1 AUTOMATED CLINICAL DIAGNOSTIC SYSTEM AND METHOD F. HOFFMANN-LA ROCHE AG (CH) 2022-06-30 WO disclosed
WO-2022117604-A1 DETECTION OF AN ANALYTE OF INTEREST BY CROSS SPRAY ESI MASS SPECTROMETRY F. HOFFMANN-LA ROCHE AG (CH) 2022-06-09 WO disclosed
WO-2022084362-A1 DETECTION OF AN ANALYTE OF INTEREST BY NANOESI MASS SPECTROMETRY F. HOFFMANN-LA ROCHE AG (CH) 2022-04-28 WO disclosed
WO-2022034018-A1 METHOD FOR DETERMINING AT LEAST ONE ANALYTE OF INTEREST F. HOFFMANN-LA ROCHE AG (CH) 2022-02-17 WO disclosed
CN-111983244-A Detection method and detection kit for four vitamins in dry blood spots 天津国科医工科技发展有限公司 2020-11-24 CN disclosed
US-20100144671-A1 Compositions and Methods for Cancer Treatment WOMEN AND INFANTS HOSPITAL OF RI, INC. (US) 2010-06-10 US disclosed
WO-2006096555-A1 COMPOSITIONS AND METHODS FOR CANCER TREATMENT WOMEN AND INFANTS HOSPITAL OF RI, INC. (US) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100144671-A1 Compositions and Methods for Cancer Treatment CYP24A1, BAX, BAD VDR 4/4885MAPT 3125/4885SMN1; SMN2 1643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.