Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.63 |
| ▸ | CSF1R | P07333 | 11/20 | 0.62 |
| ▸ | FLT3 | P36888 | 5/20 | 0.60 |
| ▸ | KIT | P10721 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3331332 | 0.91 | KDR (0.67) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3329975 | 0.90 | KDR (0.71) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3334532 | 0.89 | KDR (0.70) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3335105 | 0.87 | KDR (0.65) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3331017 | 0.87 | KDR (0.72) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3329841 | 0.86 | KDR (0.64) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3329921 | 0.86 | KDR (0.64) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3330225 | 0.86 | KDR (0.65) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL14041916 | 0.86 | KDR (0.64) | KDRCSF1RFLT3KITCYP2D6 | |
| SCHEMBL3336540 | 0.85 | KDR (0.60) | KDRCSF1RFLT3KITCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2010-06-10 | — | — | US | disclosed |
| EP-2139888-A2 | IMIDAZOÝ1,2-A¨PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | Array Biopharma, Inc. (US) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008121687-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2008-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144751-A1 | IMIDAZO[1,2-a]PYRIDINE COMPOUNDS AS RECEPTOR TYROSINE KINASE INHIBITORS | PIM1, PIM3, PIM2 | KDR 93/4885CSF1R 156/4885FLT3 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.