Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK2 | O96017 | 20/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928090 | 0.99 | CHEK2 (0.81) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL1379094 | 0.96 | CHEK2 (0.81) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL1379293 | 0.94 | CHEK2 (0.82) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL3921862 | 0.93 | CHEK2 (0.83) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL1723139 | 0.93 | CHEK2 (0.83) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL1382192 | 0.93 | CHEK2 (0.83) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL3922132 | 0.92 | CHEK2 (0.83) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL1379622 | 0.92 | CHEK2 (0.83) | CHEK2MEN1THRBKMT2A | |
| Water SCHEMBL20996301 | 0.92 | CHEK2 (0.81) | CHEK2MEN1THRBKMT2A | |
| SCHEMBL3571394 | 0.91 | CHEK2 (0.65) | CHEK2MEN1THRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | CHEK2 2880/4885MEN1 163/4885THRB 206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.