SCHEMBL333431

SCHEMBL333431

NC([C]=O)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL333432 1.00
SCHEMBL8003878 0.69
SCHEMBL6647560 0.69
SCHEMBL1918358 0.69
SCHEMBL1754723 0.69
SCHEMBL18520338 0.65
SCHEMBL10734432 0.65
SCHEMBL2364329 0.65
SCHEMBL28214409 0.64
SCHEMBL652954 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210024614-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-01-28 US disclosed
US-10745464-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-18 US disclosed
US-20190153070-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-05-23 US disclosed
US-10150806-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-12-11 US disclosed
US-20170121389-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2017-05-04 US disclosed
EP-2548967-B1 Aldehyde tags, uses thereof in site-specific protein modification UNIV CALIFORNIA (US) 2016-12-28 EP disclosed
US-9447390-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-09-20 US disclosed
US-20150072398-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2015-03-12 US disclosed
US-8846866-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2014-09-30 US disclosed
EP-2064334-B1 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION UNIV CALIFORNIA (US) 2014-06-11 EP disclosed
US-8097701-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-01-17 US disclosed
US-20110287041-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-11-24 US disclosed
US-20110250704-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-10-13 US disclosed
US-7985783-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-07-26 US disclosed
US-20110117621-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-05-19 US disclosed
WO-2009120611-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-10-01 WO disclosed
EP-2064334-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION The Regents of the University of California (US) 2009-06-03 EP disclosed
US-20080187956-A1 Modification at sulfatase motif of aldehyde tag through action of a formylglycine generating enzyme (FGE) generates formylglycine (FGly) residue NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-08-07 US disclosed
WO-2008036350-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-27 WO disclosed
US-4319918-A α-Substituted N-(trimethylcycloalkenyl)-N-alkylacetamides and their use in phytotoxic preparations CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1982-03-16 US disclosed