SCHEMBL333433

SCHEMBL333433

NC(C=O)C=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL504330 0.76
SCHEMBL17689795 0.76
SCHEMBL652954 0.74
Hydrochloric Acid SCHEMBL1444800 0.73
SCHEMBL20758665 0.73
SCHEMBL17600571 0.71
SCHEMBL4150505 0.71
SCHEMBL17600566 0.71
SCHEMBL1310902 0.69
SCHEMBL18520338 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676468-A2 ENHANCED INHIBITORS OF ENPP1 AND USES THEREOF PETRAGEN, INC. (US) 2026-01-14 EP disclosed
WO-2024187101-A2 ENHANCED INHIBITORS OF ENPP1 AND USES THEREOF Petragen, Inc. (US) 2024-09-12 WO disclosed
US-20210024614-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-01-28 US disclosed
US-10745464-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2020-08-18 US disclosed
US-10730983-B2 Biocompatible coatings and hydrogels for reducing foreign body response and fibrosis MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2020-08-04 US disclosed
US-20190153070-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2019-05-23 US disclosed
EP-3469008-A1 BIOCOMPATIBLE ZWITTERIONIC POLYMER COATINGS AND HYDROGELS FOR REDUCING FOREIGN BODY RESPONSE AND FIBROSIS Massachusetts Institute Of Technology (US) 2019-04-17 EP disclosed
CN-109563199-A Biocompatible zwitterionic polymer coatings and hydrogels for reducing foreign body reaction and fibrosis 麻省理工学院 2019-04-02 CN disclosed
US-10150806-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-12-11 US disclosed
WO-2017218507-A1 BIOCOMPATIBLE ZWITTERIONIC POLYMER COATINGS AND HYDROGELS FOR REDUCING FOREIGN BODY RESPONSE AND FIBROSIS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-12-21 WO disclosed
US-20110250704-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-10-13 US disclosed
US-7985783-B2 Aldehyde tags, uses thereof in site-specific protein modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2011-07-26 US disclosed
US-20110124914-A1 OPTICALLY ACTIVE ALPHA-AMINO ACID INTO WHICH BSH IS INTRODUCED AND METHOD FOR SYNTHESIZING THE SAME STELLA PHARMA CORPORATION (JP) 2011-05-26 US disclosed
US-20110117621-A1 Aldehyde Tags, Uses Thereof in Site-Specific Protein Modification THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2011-05-19 US disclosed
EP-1984350-B1 PYRIMIDINE DERIVATIVES USED AS PI-3 KINASE INHIBITORS NOVARTIS AG (CH) 2010-08-18 EP disclosed
WO-2009120611-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-10-01 WO disclosed
EP-2064334-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION The Regents of the University of California (US) 2009-06-03 EP disclosed
US-20080187956-A1 Modification at sulfatase motif of aldehyde tag through action of a formylglycine generating enzyme (FGE) generates formylglycine (FGly) residue NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2008-08-07 US disclosed
WO-2008036350-A2 ALDEHYDE TAGS, USES THEREOF IN SITE-SPECIFIC PROTEIN MODIFICATION THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2008-03-27 WO disclosed
EP-1310510-B1 Topologically segregated, encoded solid phase libraries AVENTIS PHARMA INC (US) 2007-07-11 EP disclosed