Benzene

Benzene

SCHEMBL333452

C=C.C=C.c1ccccc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.60
TSHR P16473 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL264923 1.00
Benzene SCHEMBL6932338 0.91 TP53 (0.50) TP53TSHR
Benzene SCHEMBL10787262 0.84 TP53 (0.43) TP53TSHR
Benzene SCHEMBL8107103 0.78 TSHR (1.00) TP53TSHR
SCHEMBL1086976 0.78 TSHR (1.00) TP53TSHR
Benzene SCHEMBL1330958 0.78
Benzene SCHEMBL10780001 0.78 TSHR (1.00) TP53TSHR
Benzene SCHEMBL8021516 0.78 TSHR (1.00) TP53TSHR
SCHEMBL1112772 0.78 TSHR (1.00) TP53TSHR
Benzene SCHEMBL8576855 0.78 TSHR (1.00) TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1856201-B1 PROCESS FOR CROSSLINKING POLYMER WITH LOW VOC-PRODUCING SILANE CROSSLINKER MOMENTIVE PERFORMANCE MAT INC (US) 2019-08-14 EP claimed
CN-109535809-A A kind of luminous paint and preparation method thereof 上海沪正实业有限公司 2019-03-29 CN claimed
EP-2241583-B1 CROSSLINKABLE SILANE-TERMINATED POLYMER AND SEALANT COMPOSITION MADE WITH SAME MOMENTIVE PERFORMANCE MAT INC (US) 2018-10-03 EP claimed
EP-1888663-B1 CROSSLINKABLE SILANE-TERMINATED POLYMER AND SEALANT COMPOSITION MADE WITH SAME MOMENTIVE PERFORMANCE MAT INC (US) 2018-08-08 EP claimed
EP-2708546-B1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom MOMENTIVE PERFORMANCE MAT INC (US) 2016-01-06 EP claimed
EP-1858968-B1 FILLER TREATMENTS UTILIZING LOW VOC SILANES MOMENTIVE PERFORMANCE MAT INC (US) 2015-12-09 EP claimed
EP-2708546-A1 Halo-Functional Silane, process for its preparation, rubber composition containing same and articles manufactured therefrom Momentive Performance Materials Inc. (US) 2014-03-19 EP claimed
EP-2207782-B1 HALO-FUNCTIONAL SILANE, PROCESS FOR ITS PREPARATION, RUBBER COMPOSITION CONTAINING SAME AND ARTICLES MANUFACTURED THEREFROM MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-26 EP claimed
EP-1270581-B1 Blocked mercaptosilane coupling agents for filled rubbers MOMENTIVE PERFORMANCE MAT INC (US) 2014-02-19 EP claimed
US-8158812-B2 Diol-derived organofunctional silane and compositions containing same Momentive Performance Marerials Inc. (US) 2012-04-17 US claimed
EP-1640183-A1 Tire with low rate volatile alcohol emission rubber tread THE GOODYEAR TIRE & RUBBER COMPANY (US) 2006-03-29 EP claimed
US-20060063879-A1 Tire with low volatile alcohol emission rubber tread with compositional limitations GOODYEAR TIRE & RUBBER COMPANY, THE 2006-03-23 US claimed
WO-2006019963-A1 DIOL-DERIVED ORGANOFUNCTIONAL SILANE AND COMPOSITIONS CONTAINING SAME GENERAL ELECTRIC COMPANY (US) 2006-02-23 WO claimed
US-20060036034-A1 Diol-derived organofunctional silane and compositions containing same GENERAL ELECTRIC COMPANY 2006-02-16 US claimed
US-20050245753-A1 Cyclic diol-derived blocked mercaptofunctional silane compositions MOMENTIVE PERFORMANCE MATERIALS INC. 2005-11-03 US claimed
CN-1643145-A Purification methods for oligonucleotides and their analogs AVECIA BIOTECHNOLOGY INC (US) 2005-07-20 CN claimed
US-20030199619-A1 Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions CROMPTON CORPORATION 2003-10-23 US claimed
EP-0877591-B1 HAIR CONDITIONING COMPOSITIONS PROCTER & GAMBLE (US) 2002-09-18 EP claimed
EP-0877592-B1 HAIR CONDITIONING COMPOSITIONS PROCTER & GAMBLE (US) 2002-09-18 EP claimed
US-6106814-A CATIONIC, CROSSLINKED POLYMER HAVING DIALKYLAMINOALKYL (METH)ACRYLATE OR QUATERNARY MONOMER(S); POLYOXYALKYLENE GLYCOL, SALT, AND POLAR SOLVENT; ATOMIZABLE, LEAVE-ON HAIR THE PROCTER & GAMBLE COMPANY (US) 2000-08-22 US claimed