Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.74 |
| ▸ | NPC1 | O15118 | 6/20 | 0.74 |
| ▸ | RAB9A | P51151 | 5/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HPGD | P15428 | 3/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | PKM | P14618 | 1/20 | 0.74 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.74 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.74 |
| ▸ | RELA | Q04206 | 1/20 | 0.74 |
| ▸ | COMT | P21964 | 2/20 | 0.62 |
| ▸ | MMP2 | P08253 | 2/20 | 0.62 |
| ▸ | MMP9 | P14780 | 2/20 | 0.62 |
| ▸ | MMP8 | P22894 | 2/20 | 0.62 |
| ▸ | MMP13 | P45452 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28370796 | 0.89 | KDM4E (0.78) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL29906196 | 0.89 | KDM4E (0.78) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL27039910 | 0.88 | KDM4E (0.61) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL16148370 | 0.88 | KDM4E (0.72) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL16147815 | 0.88 | KMT2A (0.69) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL14930221 | 0.85 | NPC1 (0.65) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17672255 | 0.85 | KDM4E (0.77) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL2617471 | 0.85 | NPC1 (1.00) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL12834035 | 0.84 | KDM4E (0.73) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL17498773 | 0.84 | MAPT (0.85) | KDM4ESMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166073-B | Benzoheterocyclic compound and composition for preventing or treating cancer disease containing the same as active ingredient | 启明大学校 产学协力团 | 2025-03-11 | — | — | CN | disclosed |
| US-20210387951-A1 | BENZO-HETEROCYCLIC COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING CANCER DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | INDUSTRY ACADEMIC COOPERATION FOUNDATION KEIMYUNG UNIVERSITY (KR) | 2021-12-16 | — | — | US | disclosed |
| CN-113166073-A | Benzoheterocyclic compounds and compositions for preventing or treating cancer diseases containing the same as active ingredient | 启明大学校产学协力团 | 2021-07-23 | — | — | CN | disclosed |
| US-8198307-B2 | Imidazole derivatives having aryl piperidine substituent, method for preparation thereof and pharmaceutical compositions containing same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2012-06-12 | — | — | US | disclosed |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387951-A1 | BENZO-HETEROCYCLIC COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING CANCER DISEASE, CONTAINING SAME AS ACTIVE INGREDIENT | VHL, BRCA1, BRD1 | KDM4E 794/4885SMN1; SMN2 888/4885NPC1 827/4885 |
| US-20100145054-A1 | IMIDAZOLE DERIVATIVES HAVING ARYL PIPERIDINE SUBSTITUENT, METHOD FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | TYR, MCHR1, MCHR2 | KDM4E 220/4885SMN1; SMN2 1895/4885NPC1 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.