Pyridine

Pyridine

SCHEMBL3335758

O=S(=O)=O.c1ccncc1.c1ccncc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.69
TSHR P16473 1/20 0.69
TDP1 Q9NUW8 1/20 0.69
NOTUM Q6P988 1/20 0.33
SLC6A3 Q01959 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
APP P05067 1/20 0.31
GAA P10253 1/20 0.31
HCAR3 P49019 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyridine SCHEMBL27819038 1.00 NAPRT (0.69) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL2077502 1.00 NAPRT (0.69) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL39580 1.00 NAPRT (0.69) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL21044758 0.96 TSHR (0.64) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL28091895 0.96 TSHR (0.64) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL27444871 0.96 TSHR (0.64) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL28773703 0.87 TSHR (0.53) NAPRTTSHRTDP1SLC6A3
Pyridine SCHEMBL11789826 0.86 NAPRT (0.60) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL27344156 0.86 TSHR (0.60) NAPRTTSHRTDP1NOTUMSLC6A3
Pyridine SCHEMBL17688281 0.86 NAPRT (0.60) NAPRTTSHRTDP1NOTUMSLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1773908-B1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION SAMYANG BIOPHARMACEUTICALS (KR) 2012-09-19 EP claimed
US-7655735-B2 Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same SAMYANG CORPORATION (KR) 2010-02-02 US claimed
JP-2008508414-A 2008-03-21 JP claimed
US-20070161753-A1 Biodegradable multi-block polymeric composition capable of sol-gel trainsition and pharmaceutical composition comprising the same SAMYANG HOLDINGS CORPORATION (KR) 2007-07-12 US claimed
EP-1773908-A1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION Samyang Corporation (KR) 2007-04-18 EP claimed
WO-2006014067-A1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION SAMYANG CORPORATION (KR) 2006-02-09 WO claimed
CN-105873930-B Novel bicyclic compounds and their use as antibacterial agents and β -lactamase inhibitors 费多拉制药公司 2019-02-19 CN disclosed
CN-105873930-A Novel bicyclic compounds and their use as antibacterial agents and beta-lactamase inhibitors 费多拉制药公司 2016-08-17 CN disclosed
EP-1773908-B1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION SAMYANG BIOPHARMACEUTICALS (KR) 2012-09-19 EP disclosed
US-7655735-B2 Biodegradable multi-block polymeric composition capable of sol-gel transition and pharmaceutical composition comprising the same SAMYANG CORPORATION (KR) 2010-02-02 US disclosed
US-20070161753-A1 Biodegradable multi-block polymeric composition capable of sol-gel trainsition and pharmaceutical composition comprising the same SAMYANG HOLDINGS CORPORATION (KR) 2007-07-12 US disclosed
EP-1773908-A1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION Samyang Corporation (KR) 2007-04-18 EP disclosed
WO-2006014067-A1 BIODEGRADABLE MULTI-BLOCK POLYMERIC COMPOSITION CAPABLE OF SOL-GEL TRANSITION SAMYANG CORPORATION (KR) 2006-02-09 WO disclosed
US-5721226-A Method for inhibiting angiogenesis using squalamine and squalamine steroid derivatives MAGAININ PHARMACEUTICALS INC. (US) 1998-02-24 US disclosed
US-5637691-A STEROIDS HAVING POLYAMINE SIDE CHAIN; BACTERICIDES, FUNGICIDES, ANTIPROTOZOA AGENTS MAGAININ PHARMACEUTICALS, INC. (US) 1997-06-10 US disclosed
EP-0749437-A1 STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR PHARMACEUTICAL USES MAGAININ PHARMACEUTICALS INC. (US) 1996-12-27 EP disclosed
EP-0688333-A1 STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS ANTIBIOTICS OR DISINFECTANTS MAGAININ PHARMACEUTICALS INC. (US) 1995-12-27 EP disclosed
WO-1995024415-A1 STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR PHARMACEUTICAL USES MAGAININ PHARMACEUTICALS INC. (US) 1995-09-14 WO disclosed
WO-1994020520-A1 STEROID DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR USE AS ANTIBIOTICS OR DISINFECTANTS MAGAININ PHARMACEUTICALS INC. (US) 1994-09-15 WO disclosed
US-4264578-A STEROL SULFATE SALTS IN SILICONE RUBBER MATRIX FOR UTERINE INSERTS ELI LILLY AND COMPANY (US) 1981-04-28 US disclosed